STK4 recombinant protein
Recombinant Human STK4 protein
Gene Names
STK4; KRS2; MST1; YSK3
Purity
>90% as determined by SDS-PAGE
Synonyms
STK4; N/A; Recombinant Human STK4 protein; Serine/threonine-protein kinase 4; Mammalian STE20-like protein kinase 1; Short name:MST-1; STE20-like kinase MST1; Serine/threonine-protein kinase Krs-2; STK4 recombinant protein
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.
Species
Homo sapiens (Human)
Reconstitution
Reconstitute in sterile water for a stock solution.
Preparation and Storage
Short Term: -20
Long Term: -80 degree C.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Long Term: -80 degree C.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Related Product Information for STK4 recombinant protein
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.
Product Categories/Family for STK4 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
52,335 Da
NCBI Official Full Name
Serine/threonine-protein kinase 4
NCBI Official Synonym Full Names
serine/threonine kinase 4
NCBI Official Symbol
STK4
NCBI Official Synonym Symbols
KRS2; MST1; YSK3
NCBI Protein Information
serine/threonine-protein kinase 4
UniProt Protein Name
Serine/threonine-protein kinase 4
UniProt Gene Name
STK4
UniProt Synonym Gene Names
KRS2; MST1; MST-1; MST1/N; MST1/C
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Product Notes
The STK4 stk4 (Catalog #AAA119942) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STK4, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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