SDS-PAGE
TLR7 recombinant protein
Recombinant Human TLR7 protein
Gene Names
TLR7; TLR7-like
Purity
>90% as determined by SDS-PAGE
Synonyms
TLR7; N/A; Recombinant Human TLR7 protein; Toll-like receptor 7; TLR7 recombinant protein
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Species
Homo sapiens (Human)
Protein Construction
A DNA sequence encoding the human TLR7 (Leu24-Ser348) was fused with His tag
Reconstitution
Reconstitute in sterile water for a stock solution.
Preparation and Storage
Store at 2°C to 8°C for one week. Store at -20°C to -80°C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.
SDS-PAGE
SDS-PAGE
Related Product Information for TLR7 recombinant protein
Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of uridine-containing single strand RNAs (ssRNAs) of viral origin or guanosine analogs. Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-containing downstream adapter MYD88 through homotypic interaction. In turn, the Myddosome signaling complex is formed involving IRAK4, IRAK1, TRAF6, TRAF3 leading to activation of downstream transcription factors NF-kappa-B and IRF7 to induce proinflammatory cytokines and interferons, respectively.
Product Categories/Family for TLR7 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted Molecular Mass: 39.04 kDa
NCBI Official Full Name
toll-like receptor 7
NCBI Official Synonym Full Names
toll-like receptor 7
NCBI Official Symbol
TLR7
NCBI Official Synonym Symbols
TLR7-like
NCBI Protein Information
toll-like receptor 7; toll-like receptor 7-like
UniProt Protein Name
Toll-like receptor 7
UniProt Gene Name
TLR7
UniProt Entry Name
TLR7_HUMAN
Similar Products
Product Notes
The TLR7 tlr7 (Catalog #AAA119922) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TLR7, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.