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IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Human Placenta Tissue)
Annexin A3 Polyclonal Antibody | anti-ANXA3 antibody
Anti-Annexin A3 Antibody
Gene Names
ANXA3; ANX3
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen Affinity Purified
Synonyms
Annexin A3; Polyclonal Antibody; Anti-Annexin A3 Antibody; 2-cyclic phosphate 2-phosphohydrolase; 35-alpha calcimedin; Annexin III; Annexin-3; ANX3; ANXA 3; Anxa3; ANXA3_HUMAN; Inositol 1 2 cyclic phosphate 2 phosphohydrolase; Inositol 1; Lipocortin III; OTTHUMP00000160701; OTTHUMP00000219237; OTTHUMP00000219238; PAP III; PAP-III; Placental anticoagulant protein III; annexin A3; anti-ANXA3 antibody
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
323
Applicable Applications for anti-ANXA3 antibody
Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin
Application Notes
Western Blot Concentration: 0.1-0.5ug/ml
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml
Immunohistochemistry (IHC) Formalin Concentration: 0.5-1ug/ml
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml
Immunohistochemistry (IHC) Formalin Concentration: 0.5-1ug/ml
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3 (153-184aa RKALLTLADGRRDESLKVDEHLAKQDAQILYK), different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Human Placenta Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Human Placenta Tissue)
IHC (Immunohistchemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Rat Cardiac Muscle Tissue)
IHC (Immunohistchemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Mouse Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(F)IHC(F): Mouse Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(P)IHC(P): Mouse Cardiac Muscle Tissue)
IHC (Immunohistochemistry)
(Anti- Annexin A3 Picoband antibody, AAA11641, IHC(P)IHC(P): Mouse Cardiac Muscle Tissue)
WB (Western Blot)
(Anti- Annexin A3 Picoband antibody, AAA11641, Western blottingAll lanes: Anti Annexin A3 (AAA11641) at 0.5ug/mlLane 1: Rat Spleen Tissue Lysate at 50ugLane 2: Rat Stomach Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: 22RV1 Whole Cell Lysate at 40ugLane 5: A549 Whole Cell Lysate at 40ugLane 6: MCF-7 Whole Cell Lysate at 40ugLane 7: SW620 Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD)
WB (Western Blot)
(Anti- Annexin A3 Picoband antibody, AAA11641, Western blottingAll lanes: Anti Annexin A3 (AAA11641) at 0.5ug/mlLane 1: Rat Spleen Tissue Lysate at 50ugLane 2: Rat Stomach Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: 22RV1 Whole Cell Lysate at 40ugLane 5: A549 Whole Cell Lysate at 40ugLane 6: MCF-7 Whole Cell Lysate at 40ugLane 7: SW620 Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD)
Related Product Information for anti-ANXA3 antibody
Description: Rabbit IgG polyclonal antibody for Annexin A3(ANXA3) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
References
1. Bianchi C, et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am J Pathol, 2010 Apr. 2. Jung EJ, et al. Decreased annexin A3 expression correlates with tumor progression in papillary thyroid cancer. Proteomics Clin Appl, 2010 May. 3. Yan X, et al. Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer. Cancer Res, 2010 Feb 15.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,375 Da
NCBI Official Full Name
annexin A3
NCBI Official Synonym Full Names
annexin A3
NCBI Official Symbol
ANXA3
NCBI Official Synonym Symbols
ANX3
NCBI Protein Information
annexin A3
UniProt Protein Name
Annexin A3
UniProt Gene Name
ANXA3
UniProt Synonym Gene Names
ANX3; PAP-III
UniProt Entry Name
ANXA3_HUMAN
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Product Notes
The ANXA3 anxa3 (Catalog #AAA11641) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Annexin A3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Annexin A3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin. Western Blot Concentration: 0.1-0.5ug/ml Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml Immunohistochemistry (IHC) Formalin Concentration: 0.5-1ug/ml. Researchers should empirically determine the suitability of the ANXA3 anxa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Annexin A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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