Background: Transforming growth factor-beta 2 (TGF-beta2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. It is known to suppress the effects of interleukin dependent T-cell tumors. It is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma. In 2004, Gottanka found that TGF-beta2 reduced outflow facility when perfused into cultured Mouse anterior segments. Furthermore, TGF-beta2 affected the extracellular matrix of the trabecular meshwork in a manner that was consistent with the observed reduction in outflow facility.
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The Mouse TGFbeta2 tgfb2 (Catalog #AAA13489) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA13489 ELISA Kit recognizes Mouse TGFbeta2. AAA Biotech's TGFbeta2 can be used in a range of immunoassay formats including, but not limited to, Quantitative sELISA (EIA). For quantitative detection of TGF-beta2 in mouse serum, plasma, urine, cell culture supernatant or tissue samples. Researchers should empirically determine the suitability of the TGFbeta2 tgfb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGFbeta2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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