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IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using RIPK1/RIP Rabbit pAb.)
Rabbit RIPK1 Polyclonal Antibody | anti-RIPK1 antibody
RIPK1 Rabbit Polyclonal Antibody
Gene Names
RIPK1; RIP; RIP1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity purification
Synonyms
RIPK1; Polyclonal Antibody; RIPK1 Rabbit Polyclonal Antibody; RIP; RIP-1; RIP1; anti-RIPK1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applicable Applications for anti-RIPK1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
IHC: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant fusion protein of human RIPK1/RIP (NP_003795.2).
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using RIPK1/RIP Rabbit pAb.)
IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using RIPK1/RIP Rabbit pAb.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human tonsil using RIPK1/RIP antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human tonsil using RIPK1/RIP antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse spleen using RIPK1/RIP antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse spleen using RIPK1/RIP antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded rat lung using RIPK1/RIP antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded rat lung using RIPK1/RIP antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using RIPK1/RIP antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using RIPK1/RIP antibody.)
WB (Western Blot)
(Western blot analysis of extracts of C6 cells, using RIPK1/RIP antibody.)
WB (Western Blot)
(Western blot analysis of extracts of C6 cells, using RIPK1/RIP antibody.)
Related Product Information for anti-RIPK1 antibody
3'-5' DNA helicase and substrate-recognition component of the SCF(FBH1 E3 ubiquitin ligase complex that plays a key role in response to stalled/damaged replication forks. Involved in genome maintenance by acting as an anti-recombinogenic helicase and preventing extensive strand exchange during homologous recombination: promotes RAD51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination. Also promotes cell death and DNA double-strand breakage in response to replication stress: together with MUS81, promotes the endonucleolytic DNA cleavage following prolonged replication stress via its helicase activity, possibly to eliminate cells with excessive replication stress. Plays a major role in remodeling of stalled DNA forks by catalyzing fork regression, in which the fork reverses and the two nascent DNA strands anneal. In addition to the helicase activity, also acts as the substrate-recognition component of the SCF(FBH1 E3 ubiquitin ligase complex, a complex that mediates ubiquitination of RAD51, leading to regulate RAD51 subcellular location.
Product Categories/Family for anti-RIPK1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70,733 Da
NCBI Official Full Name
receptor-interacting serine/threonine-protein kinase 1
NCBI Official Synonym Full Names
receptor (TNFRSF)-interacting serine-threonine kinase 1
NCBI Official Symbol
RIPK1
NCBI Official Synonym Symbols
RIP; RIP1
NCBI Protein Information
receptor-interacting serine/threonine-protein kinase 1; RIP-1; cell death protein RIP; receptor interacting protein; receptor-interacting protein 1; serine/threonine-protein kinase RIP
UniProt Protein Name
Receptor-interacting serine/threonine-protein kinase 1
UniProt Gene Name
RIPK1
UniProt Synonym Gene Names
RIP; RIP1; RIP-1
UniProt Entry Name
RIPK1_HUMAN
Similar Products
Product Notes
The RIPK1 ripk1 (Catalog #AAA30689) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RIPK1 Rabbit Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RIPK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the RIPK1 ripk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIPK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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