Structure
(Antifungal agent 15, CAS 2639531-53-4)
BRK inhibitor P21d hydrochloride Biochemical
BRK inhibitor P21d hydrochloride
Purity
98%
Synonyms
BRK inhibitor P21d hydrochloride; N/A; BRK inhibitor P21d hydrochloride biochemical
Purity/Purification
98%
CAS
2250025-98-8
Targets&IC50
Aurora B:20 uM (IC50), Brk:30 nM (IC50), p-SAM68:52 nM (IC50), Lck:20 uM (IC50)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
BRK inhibitor P21d hydrochloride (compound 21d) has much better permeability (CACO-2:314 nm/s) and PK profile (rat, po, 10 mpk, AUC 0-6h =31.1 uM/h,C 6h =3.5 uM)[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Antifungal agent 15, CAS 2639531-53-4)
Structure
(Antifungal agent 15, CAS 2639531-53-4)
Structure
(Antifungal agent 15, CAS 2639531-53-4)
Structure
(Antifungal agent 15, CAS 2639531-53-4)
Related Product Information for BRK inhibitor P21d hydrochloride biochemical
BRK inhibitor P21d hydrochloride is a potent breast tumor kinase (BRK/PTK6) inhibitor with an IC 50 of 30 nM. BRK inhibitor P21d hydrochloride inhibits p-SAM68 with an IC 50 of 52 nM. BRK inhibitor P21d hydrochloride can be used to evaluate the in vivo activity of BRK inhibitors in xenograft breast tumor models.
References
1. Chen YJ, et al. Antifungal Exploration of Quinoline Derivatives against Phytopathogenic Fungi Inspired by Quinine Alkaloids. J Agric Food Chem. 2021 Oct 20;69(41):12156-12170.
Similar Products
Product Notes
The BRK inhibitor P21d hydrochloride (Catalog #AAA228264) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BRK inhibitor P21d hydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.