Structure
Forskolin Biochemical
Forskolin
Applications
Functional Assay
Purity
>98%
Synonyms
Forskolin; N/A; Coleonol; colforsin; NKH-477; NSC 375489; [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate; Forskolin biochemical
Purity/Purification
>98%
Form/Format
Crystalline solid
Applicable Applications for Forskolin biochemical
FA (Functional Assay)
Molecular Formula
C22H34O7
CAS Number
66575-29-9
Preparation and Storage
Product should be kept at -20 degree C.
Soluble in organic solvents such as ethanol or DMSO.
Soluble in organic solvents such as ethanol or DMSO.
Structure
Structure
Related Product Information for Forskolin biochemical
Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cyclic AMP (cAMP). It has vasodilator and hypotensive properties and can be used to induce neuronal differentiation in stem cells. In combination with other small molecules, it is also reported to be utilized in the chemical reprogramming of embryonic fibroblasts to induced pluripotent stem cells.
References
Seamon, K. B., & Daly, J. W. (1980). Forskolin: a unique diterpene activator of cyclic AMP-generating systems. Journal of cyclic nucleotide research, 7(4), 201-224.
Laurenza, A., Sutkowski, E. M., & Seamon, K. B. (1989). Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action. Trends in Pharmacological Sciences, 10(11), 442-447.
Shamblott, M. J., Axelman, J., Wang, S., Bugg, E. M., Littlefield, J. W., Donovan, P. J.,... & Gearhart, J. D. (1998). Derivation of pluripotent stem cells from cultured human primordial germ cells. Proceedings of the National Academy of Sciences, 95(23), 13726-13731.
Laurenza, A., Sutkowski, E. M., & Seamon, K. B. (1989). Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action. Trends in Pharmacological Sciences, 10(11), 442-447.
Shamblott, M. J., Axelman, J., Wang, S., Bugg, E. M., Littlefield, J. W., Donovan, P. J.,... & Gearhart, J. D. (1998). Derivation of pluripotent stem cells from cultured human primordial germ cells. Proceedings of the National Academy of Sciences, 95(23), 13726-13731.
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Product Notes
The Forskolin (Catalog #AAA79339) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Forskolin can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay). Researchers should empirically determine the suitability of the Forskolin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Forskolin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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