Structure
(Luteinizing hormone (human), CAS 39341-83-8)
PROTAC BRD4 Degrader-10 Biochemical
PROTAC BRD4 Degrader-10
Purity
98%
Synonyms
PROTAC BRD4 Degrader-10; N/A; PROTAC BRD4 Degrader-10 biochemical
Purity/Purification
98%
CAS
2417370-49-9
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Luteinizing hormone (human), CAS 39341-83-8)
Structure
(Luteinizing hormone (human), CAS 39341-83-8)
Structure
(Luteinizing hormone (human), CAS 39341-83-8)
Structure
(Luteinizing hormone (human), CAS 39341-83-8)
Related Product Information for PROTAC BRD4 Degrader-10 biochemical
PROTAC BRD4 Degrader-10 (compound 8b) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC 50 of 1.3 nM and 18 nM, respectively.
References
1. Laura Riccetti, et al. Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors. Sci Rep. 2017 Apr 19;7(1):940.
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Product Notes
The PROTAC BRD4 Degrader-10 (Catalog #AAA228430) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PROTAC BRD4 Degrader-10, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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