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Botulinum neurotoxin type E Recombinant Protein | BXE recombinant protein

Recombinant Clostridium butyricum Botulinum neurotoxin type E

Reactivity
CLOBU
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Botulinum neurotoxin type E; N/A; Recombinant Clostridium butyricum Botulinum neurotoxin type E; BXE recombinant protein
Ordering
Host
E Coli
Reactivity
CLOBU
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer 50% glycerol
Sequence Positions
Full Length of Botulinum neurotoxin E light chain, 2-422aa
Sequence
PTINSFNYNDPVNNRTILYIKPGGCQQFYKSFNIMKNIWIIPERNVIGTIPQDFLPPTSLKNGDSSYYDPNYLQSDQEKDKFLKIVTKIFNRINDNLSGRILLEELSKANPYLGNDNTPDGDFIINDASAVPIQFSNGSQSILLPNVIIMGAEPDLFETNSSNISLRNNYMPSNHGFGSIAIVTFSPEYSFRFKDNSMNEFIQDPALTLMHELIHSLHGLYGAKGITTKYTITQKQNPLITNIRGTNIEEFLTFGGTDLNIITSAQSNDIYTNLLADYKKIASKLSKVQVSNPLLNPYKDVFEAKYGLDKDASGIYSVNINKFNDIFKKLYSFTEFDLATKFQVKCRQTYIGQYKYFKLSNLLNDSIYNISEGYNINNLKVNFRGQNANLNPRIITPITGRGLVKKIIRFCKNIVSVKGIR
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C,-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C,-80 degree C.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for BXE recombinant protein
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
63.7 kDa
NCBI Official Full Name
Botulinum neurotoxin type E
UniProt Protein Name
Botulinum neurotoxin type E
UniProt Gene Name
BoNT/E
UniProt Synonym Gene Names
BoNT/E

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Product Notes

The BXE bont/e (Catalog #AAA309750) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length of Botulinum neurotoxin E light chain, 2-422aa. The Recombinant Clostridium butyricum Botulinum neurotoxin type E reacts with CLOBU and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: PTINSFNYND PVNNRTILYI KPGGCQQFYK SFNIMKNIWI IPERNVIGTI PQDFLPPTSL KNGDSSYYDP NYLQSDQEKD KFLKIVTKIF NRINDNLSGR ILLEELSKAN PYLGNDNTPD GDFIINDASA VPIQFSNGSQ SILLPNVIIM GAEPDLFETN SSNISLRNNY MPSNHGFGSI AIVTFSPEYS FRFKDNSMNE FIQDPALTLM HELIHSLHGL YGAKGITTKY TITQKQNPLI TNIRGTNIEE FLTFGGTDLN IITSAQSNDI YTNLLADYKK IASKLSKVQV SNPLLNPYKD VFEAKYGLDK DASGIYSVNI NKFNDIFKKL YSFTEFDLAT KFQVKCRQTY IGQYKYFKLS NLLNDSIYNI SEGYNINNLK VNFRGQNANL NPRIITPITG RGLVKKIIRF CKNIVSVKGI R. It is sometimes possible for the material contained within the vial of "Botulinum neurotoxin type E, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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