Application Data
(Image: Blots of crude rat brain extract stained with Doublecortin. Protocol on datasheet.)
Doublecortin/DCX Antibody | anti-DCX antibody
Doublecortin/DCX, Monoclonal Antibody, Mouse
Gene Names
DCX; DC; DBCN; LISX; SCLH; XLIS
Reactivity
Bovine, Human, Mouse, Porcine, Rat
Applications
Western Blot, Immunofluorescence
Synonyms
Doublecortin/DCX; N/A; Doublecortin/DCX, Monoclonal Antibody, Mouse; anti-DCX antibody
Reactivity
Bovine, Human, Mouse, Porcine, Rat
Form/Format
Supernatant - Liquid
Sequence Length
360
Applicable Applications for anti-DCX antibody
WB (Western Blot), IF (Immunofluorescence)
Type Info
Mouse IgG
Immunogen
Recombinant full length human Doublecortin purified from E Coli.
Application Data
(Image: Blots of crude rat brain extract stained with Doublecortin. Protocol on datasheet.)
Application Data
(Image: Blots of crude rat brain extract stained with Doublecortin. Protocol on datasheet.)
Application Data
(Image: E18 hippocampal neurons stained with MAPT (red) and Doublecortin (green). The two proteins overlap in the proximal dendrites, but doublecortin is more abundant in the growth cones and periphery. As a result, the periphery appears green while the more proximal regions of the cells are yellow. The single longer process of this cell, presumably an axon, has a low doublecortin content and so appears red. Blue staining is the nuclear DNA. Protocol on datasheet.)
Application Data
(Image: E18 hippocampal neurons stained with MAPT (red) and Doublecortin (green). The two proteins overlap in the proximal dendrites, but doublecortin is more abundant in the growth cones and periphery. As a result, the periphery appears green while the more proximal regions of the cells are yellow. The single longer process of this cell, presumably an axon, has a low doublecortin content and so appears red. Blue staining is the nuclear DNA. Protocol on datasheet.)
Related Product Information for anti-DCX antibody
Doublecortin (DCX) has a molecular weight of about 45kDa. The protein contains two domains, each about 90 amino acids long, which are believed to function in binding to microtubules, a C-terminal serine and proline rich region which may become phosphorylated in vivo. DCX is expressed very early in neuronal development, as neuroblasts become post-mitotic, but is lost as neurons mature. Developing neurons start to lose DCX expression about the time that they begin to express NeuN, a neuronal specific RNA binding protein characteristic of more mature neurons. Antibodies to DCX are used to identify stem cells in sections and in tissue culture, and to see if neurogenesis is taking place.
Product Categories/Family for anti-DCX antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
40,044 Da
NCBI Official Full Name
doublecortin
NCBI Official Synonym Full Names
doublecortin
NCBI Official Symbol
DCX
NCBI Official Synonym Symbols
DC; DBCN; LISX; SCLH; XLIS
NCBI Protein Information
neuronal migration protein doublecortin
UniProt Protein Name
Neuronal migration protein doublecortin
UniProt Gene Name
DCX
UniProt Synonym Gene Names
DBCN; LISX; Lis-X
UniProt Entry Name
DCX_HUMAN
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Product Notes
The DCX dcx (Catalog #AAA76430) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Doublecortin/DCX, Monoclonal Antibody, Mouse reacts with Bovine, Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Doublecortin/DCX can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the DCX dcx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Doublecortin/DCX, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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