Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human NT3 at 2 ug/ml (100 ul/well) can bind human TrkB-Fch. The EC50 of human TrkB-Fch is 120-350 ng/mL.)
Neurotrophin 3 Active Protein | NTF3 active protein
Neurotrophin 3 Protein, Human, Recombinant
Gene Names
NTF3; NT3; HDNF; NGF2; NGF-2
Purity
>90% as determined by SDS-PAGE
Synonyms
Neurotrophin 3; N/A; Neurotrophin 3 Protein, Human, Recombinant; Human NTF3/Neurotrophin 3 Protein; HDNF Protein, Human; NGF-2 Protein, Human; NGF2 Protein, Human; NT-3 Protein, Human; NT3 Protein, Human; neurotrophin 3; NTF3 active protein
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH5.2. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Tyr139-Thr257
Species
Human
Predicted N Terminal
Met
Tag
Native
Protein Construction
A DNA sequence encoding the human NT3 (P20783-1)(Tyr139-Thr257) was expressed and purified.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Activity
Measured by its binding ability in a functional ELISA. Immobilized human NT3 at 2ug/ml (100uL/well) can bind human TrkB-Fch. The EC50 of human TrkB-Fch is 120-350ng/mL.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human NT3 at 2 ug/ml (100 ul/well) can bind human TrkB-Fch. The EC50 of human TrkB-Fch is 120-350 ng/mL.)
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human NT3 at 2 ug/ml (100 ul/well) can bind human TrkB-Fch. The EC50 of human TrkB-Fch is 120-350 ng/mL.)
SDS-PAGE
SDS-PAGE
Related Product Information for NTF3 active protein
Background: NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,355 Da
NCBI Official Full Name
neurotrophin-3 isoform 1 preproprotein
NCBI Official Synonym Full Names
neurotrophin 3
NCBI Official Symbol
NTF3
NCBI Official Synonym Symbols
NT3; HDNF; NGF2; NGF-2
NCBI Protein Information
neurotrophin-3; NT-3; neurotrophic factor; nerve growth factor 2
UniProt Protein Name
Neurotrophin-3
UniProt Gene Name
NTF3
UniProt Synonym Gene Names
NT-3; NGF-2
UniProt Entry Name
NTF3_HUMAN
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Product Notes
The NTF3 ntf3 (Catalog #AAA257863) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Tyr139-Thr 257. It is sometimes possible for the material contained within the vial of "Neurotrophin 3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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