Bioactivity
(MagnifyHuman Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc in a functional ELISA assay.)
Fc gamma RIIIA/CD16a Recombinant Protein | FcgammaRIIIA/CD16a recombinant protein
Recombinant human Fc gamma RIIIA/CD16a protein
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Fc gamma RIIIA/CD16a; N/A; Recombinant human Fc gamma RIIIA/CD16a protein; Low affinity immunoglobulin gamma Fc region receptor III-A; CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20; FcgammaRIIIA/CD16a recombinant protein
Host
Baculovirus
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Concentration
0.25mg/ml (determined by absorbance at 280nm) (varies by lot)
Sequence Positions
18-208aa
Sequence
Applicable Applications for FcgammaRIIIA/CD16a recombinant protein
Bioactivity, SDS-PAGE
Species
Human
Tag
His-Tag
Predicted Nterm
Ala
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity
Measured by its binding ability in a functional ELISA with Human IgG1 Fc.
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Bioactivity
(MagnifyHuman Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc in a functional ELISA assay.)
Bioactivity
(MagnifyHuman Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc in a functional ELISA assay.)
SDS-PAGE
(Magnify3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
SDS-PAGE
(Magnify3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for FcgammaRIIIA/CD16a recombinant protein
FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for FcgammaRIIIA/CD16a recombinant protein
References
Ravetch JV., et al. (1989) J Exp Med. 170:481-497.;; Ferrara C., et al. (2011) Proc Natl Acad Sci U S A. 108:12669-12674.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
22.8kDa (200aa)
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-A
UniProt Gene Name
FCGR3A
UniProt Synonym Gene Names
CD16A; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa
UniProt Entry Name
FCG3A_HUMAN
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Product Notes
The FcgammaRIIIA/CD16a fcgr3a (Catalog #AAA48428) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-208aa. AAA Biotech's Fc gamma RIIIA/CD16a can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the FcgammaRIIIA/CD16a fcgr3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below:Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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