FCM/FACS (Flow Cytometry)
(Flow cytometry surface staining patterns of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 ?g/ml, left) or mouse IgG2a isotype control (MOPC-173) PE antibody (concentration in sample 5 ?g/ml, same as CD158z PE concentration, right).)
anti-Human CD158z Antibody | anti-CD158z antibody
Anti-Hu CD158z PE
Gene Names
KIR3DL3; KIR44; KIRC1; CD158Z; KIR3DL7
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Synonyms
CD158z; N/A; Anti-Hu CD158z PE; killer cell immunoglobulin like receptor, three Ig; KIR3DL3; anti-CD158z antibody
Reactivity
Human
Isotype
Mouse IgG2a
Clone Number
CH21
Specificity
The mouse monoclonal antibody CH21 recognizes an extracellular epitope of human CD158z (KIR3DL3), a transmembrane glycoprotein of killer cell inhibitory receptor family.
Form/Format
PE
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Concentration
0.1mg/ml (varies by lot)
Applicable Applications for anti-CD158z antibody
FCM/FACS (Flow Cytometry)
Immunogen
human CD158z transfectants
Preparation and Storage
Store at 2-8 degree C. Protect from prolonged exposure to light. Do not freeze.
FCM/FACS (Flow Cytometry)
(Flow cytometry surface staining patterns of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 ?g/ml, left) or mouse IgG2a isotype control (MOPC-173) PE antibody (concentration in sample 5 ?g/ml, same as CD158z PE concentration, right).)
FCM/FACS (Flow Cytometry)
(Flow cytometry surface staining patterns of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 ?g/ml, left) or mouse IgG2a isotype control (MOPC-173) PE antibody (concentration in sample 5 ?g/ml, same as CD158z PE concentration, right).)
FCM/FACS (Flow Cytometry)
(Separation of CD158z positive cells (red-filled) from CD158z negative cells (black-dashed) in flow cytometry analysis (surface staining) of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 ?g/ml).)
FCM/FACS (Flow Cytometry)
(Separation of CD158z positive cells (red-filled) from CD158z negative cells (black-dashed) in flow cytometry analysis (surface staining) of KIR3DL3 (CD158z) transfected HEK-293 suspension stained using anti-human CD158z (CH21) PE antibody (concentration in sample 5 ?g/ml).)
Related Product Information for anti-CD158z antibody
CD158z (KIR3DL3)is one of killer cell inhibitory receptors. It has three extracellular immunoglobulin-like domains and a long cytoplasmic tail, which, however, contains only one ITIM. Like other KIRs, CD158z is highly polymorphic, but it seems that its immunoglobulin-like domains are quite conserved among high primates.
References
*Trundley AE, Hiby SE, Chang C, Sharkey AM, Santourlidis S, Uhrberg M, Trowsdale J, Moffett A: Molecular characterization of KIR3DL3. Immunogenetics 2006 Jan;57(12):904-16., URL: https://pubmed.ncbi.nlm.nih.gov/16391939/,
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,928 Da
NCBI Official Full Name
killer cell immunoglobulin-like receptor 3DL3
NCBI Official Synonym Full Names
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
NCBI Official Symbol
KIR3DL3
NCBI Official Synonym Symbols
KIR44; KIRC1; CD158Z; KIR3DL7
NCBI Protein Information
killer cell immunoglobulin-like receptor 3DL3; killer cell inhibitory receptor 1; CD158 antigen-like family member Z; killer cell Ig-like receptor KIR3DL7
UniProt Protein Name
Killer cell immunoglobulin-like receptor 3DL3
UniProt Gene Name
KIR3DL3
UniProt Synonym Gene Names
CD158Z; KIR3DL7; KIRC1
UniProt Entry Name
KI3L3_HUMAN
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Product Notes
The CD158z kir3dl3 (Catalog #AAA129297) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hu CD158z PE reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD158z can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD158z kir3dl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD158z, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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