anti-Human CD37 Antibody | anti-CD37 antibody

Anti-Hu CD37 PE

Cat. Num. AAA129249

• Gene Names: CD37; GP52-40; TSPAN26
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay
• Synonyms: CD37; N/A; Anti-Hu CD37 PE; CD37 molecule; GP52-40; tetraspanin 26; anti-CD37 antibody

• Reactivity: Human
• Isotype: Mouse IgG1 kappa
• Clone Number: MB-1
• Specificity: The mouse monoclonal antibody MB-1 recognizes an extracellular epitope of CD37, a tetraspanin family transmembrane glycoprotein.
• Form/Format: PE; Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.; Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Applicable Applications for anti-CD37 antibody: FCM/FACS (Flow Cytometry)
• Immunogen: lymphomatous lymph node cells
• Preparation and Storage: Store at 2-8 degree C. Protect from prolonged exposure to light. Do not freeze.

FCM/FACS (Flow Cytometry)

(Separation of human CD37 positive CD19 positive lymphocytes (red-filled) CD37 negative CD19 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD37 (MB-1) PE antibody (10 ?l reagent / 100 ?l of peripheral whole blood).)

FCM/FACS (Flow Cytometry)

(Flow cytometry multicolor surface staining of human gated lymphocytes stained using anti-human CD37 (MB-1) PE antibody (10 ?l reagent / 100 ?l of peripheral whole blood) and anti-human CD19 (LT19) APC antibody (10 ?l reagent / 100 ?l of peripheral whole blood).)

FCM/FACS (Flow Cytometry)

(Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD37 (MB-1) PE antibody (10 ?l reagent / 100 ?l of peripheral whole blood).)

Related Product Information for anti-CD37 antibody

CD37 is a 40-64 kDa tetraspanin family glycoprotein, which forms complexes in the B cell membrane with MHC class II, CD53, CD81, and CD82. It is expressed highly on mature B cells and neoplastic B cells, but it is lost on plasma cells, as well as on pro-B cells. Lower expression was detected on monocytes, macrophages, and dendritic cells.

References

*Link MP, Bindl J, Meeker TC, Carswell C, Doss CA, Warnke RA, Levy R: A unique antigen on mature B cells defined by a monoclonal antibody. J Immunol. 1986 Nov 1;137(9):3013-8., URL: https://pubmed.ncbi.nlm.nih.gov/3489782/,*Press OW, Eary JF, Badger CC, Martin PJ, Appelbaum FR, Levy R, Miller R, Brown S, Nelp WB, Krohn KA: Treatment of refractory non-Hodgkin's lymphoma with radiolabeled MB-1 (anti-CD37) antibody. J Clin Oncol. 1989 Aug;7(8):1027-38., URL: https://pubmed.ncbi.nlm.nih.gov/2666588/,

NCBI and Uniprot Product Information

• NCBI GI #: 91807110
• NCBI GeneID: 951
• NCBI Accession #: NP_001035120.1
• NCBI GenBank Nucleotide #: NM_001040031.1
• UniProt Accession #: P11049; Q3KPF9; B4DVC1
• Molecular Weight: 22,563 Da
• NCBI Official Full Name: leukocyte antigen CD37 isoform B
• NCBI Official Synonym Full Names: CD37 molecule
• NCBI Official Symbol: CD37
• NCBI Official Synonym Symbols: GP52-40; TSPAN26
• NCBI Protein Information: leukocyte antigen CD37
• UniProt Protein Name: Leukocyte antigen CD37
• UniProt Gene Name: CD37
• UniProt Synonym Gene Names: TSPAN26; Tspan-26
• UniProt Entry Name: CD37_HUMAN