Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Nt-3 Growth Factor Receptor, NTRK3 ELISA Kit | NTRK3 elisa kit
Human Nt-3 Growth Factor Receptor, NTRK3 Primacu ELISA Kit
Gene Names
NTRK3; TRKC; gp145(trkC)
Reactivity
Human
Synonyms
Nt-3 Growth Factor Receptor, NTRK3; N/A; Human Nt-3 Growth Factor Receptor, NTRK3 Primacu ELISA Kit; NT-3 growth factor receptor; TrkC; TRKC; NTRK3 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
62.5-4000pg/mL
Sensitivity
12.83pg/mL
Standard Solution
40ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for NTRK3 elisa kit
NT-3 growth factor receptor is also known as neurotrophic tyrosine kinase receptor type 3 or TrkC tyrosine kinase or Trk-C receptor, is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC/NTRK3 is widely expressed in the developing and adult nervous system. In later embryonic development, TrkC/NTRK3 is expressed in various structures of the CNS including the caudate-putamen, septal nuclei, cerebellum, and brainstem. Other neurotrophins include nerve growth factor(NGF), neurotrophin-3 and neurotrophin-4. In the PNS, The trkC hybridization appears to correlate, both temporally and spatially, with the outgrowth of axons toward their peripheral targets. TrkC/NTRK3 is widely expressed in the three identified branches of the mammalian nervous system and appears to correlate with the expression of NT-3, its cognate ligand. The apparent colocalization of trkC transcripts with NT-3 raises the possibility this neurotrophin exerts its trophic effects by a paracrine and/or autocrine mechanism. Signaling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in the TrkC encoding gene have been associated with medulloblastomas, secretory breast carcinomas, and other cancers. Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy
Product Categories/Family for NTRK3 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
94,428 Da
NCBI Official Full Name
NT-3 growth factor receptor isoform a
NCBI Official Synonym Full Names
neurotrophic tyrosine kinase, receptor, type 3
NCBI Official Symbol
NTRK3
NCBI Official Synonym Symbols
TRKC; gp145(trkC)
NCBI Protein Information
NT-3 growth factor receptor; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
UniProt Protein Name
NT-3 growth factor receptor
UniProt Gene Name
NTRK3
UniProt Synonym Gene Names
TRKC; Trk-C
UniProt Entry Name
NTRK3_HUMAN
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Product Notes
The Human NTRK3 ntrk3 (Catalog #AAA124160) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124160 ELISA Kit recognizes Human NTRK3. It is sometimes possible for the material contained within the vial of "Nt-3 Growth Factor Receptor, NTRK3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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