IHC (Immunohistochemisry)
(Anti-TrkC antibody, AAA45407, IHC(P)IHC(P): Rat Brain Tissue)
Rabbit TrkC Polyclonal Antibody | anti-NTRK3 antibody
Anti-TrkC antibody
Gene Names
NTRK3; TRKC; gp145(trkC)
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
TrkC, Antibody; Anti-TrkC antibody; NT-3 growth factor receptor; neurotrophic tyrosine kinase, receptor, type 3; EC 2.7.10.1 antibody; ETS related protein neurotrophic receptor tyrosine kinase fusion antibody; ETV6 NTRK3 fusion antibody; GP145 TrkC antibody; gp145(trkC) antibody; GP145-TrkC antibody; GP145TrkC antibody; Neurotrophic tyrosine kinase receptor type 3 antibody; Neurotrophin 3 receptor antibody; NT 3 growth factor receptor antibody; NT 3 growth factor receptor precursor antibody; NT 3 receptor antibody; NT-3 growth factor receptor antibody; Ntrk3 antibody; NTRK3_HUMAN antibody; OTTHUMP00000192915 antibody; TRK C antibody; Trk-C antibody; TrkC tyrosine kinase antibody; Tyrosine kinase receptor C antibody; anti-NTRK3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
839
Applicable Applications for anti-NTRK3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human TrkC (167-182aa DIRWMQLWQEQGEAKL), different from the related mouse and rat sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti-TrkC antibody, AAA45407, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohistochemisry)
(Anti-TrkC antibody, AAA45407, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-TrkC antibody, AAA45407, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-TrkC antibody, AAA45407, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-TrkC antibody, AAA45407, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Mouse Brain Tissue LysateLane 3: U87 Cell LysateLane 4: SHG Cell LysateLane 5: NEURO Cell Lysate)
WB (Western Blot)
(Anti-TrkC antibody, AAA45407, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Mouse Brain Tissue LysateLane 3: U87 Cell LysateLane 4: SHG Cell LysateLane 5: NEURO Cell Lysate)
Related Product Information for anti-NTRK3 antibody
Description: Rabbit IgG polyclonal antibody for NT-3 growth factor receptor(NTRK3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al.(1994) mapped the NTRK3 gene to 15q24-q25. Lamballe et al.(1991) isolated and characterized TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain; in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, Muinos-Gimeno et al.(2009) demonstrated that 5 miRNAs regulate the truncated form of NTRK3.
Background: NTRK3(Neurotrophic Tyrosine Kinase Receptor Type 3), also known as TRKC, is a protein that in humans is encoded by the NTRK3 gene. By PCR analysis of a somatic cell hybrid panel and by fluorescence in situ hybridization with the cDNA clone, McGregor et al.(1994) mapped the NTRK3 gene to 15q24-q25. Lamballe et al.(1991) isolated and characterized TRKC, a member of the TRK family of tyrosine protein kinase genes. They found that TRKC is preferentially expressed in the brain; in situ hybridization studies showed transcripts in the hippocampus, cerebral cortex, and the granular cell layer of the cerebellum. By functional studies in HeLa cells, Muinos-Gimeno et al.(2009) demonstrated that 5 miRNAs regulate the truncated form of NTRK3.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
91,833 Da
NCBI Official Full Name
NT-3 growth factor receptor
NCBI Official Synonym Full Names
neurotrophic tyrosine kinase, receptor, type 3
NCBI Official Symbol
NTRK3
NCBI Official Synonym Symbols
TRKC; gp145(trkC)
NCBI Protein Information
NT-3 growth factor receptor; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein
UniProt Protein Name
NT-3 growth factor receptor
UniProt Gene Name
NTRK3
UniProt Synonym Gene Names
TRKC; Trk-C
UniProt Entry Name
NTRK3_HUMAN
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Product Notes
The NTRK3 ntrk3 (Catalog #AAA45407) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TrkC antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TrkC can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NTRK3 ntrk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TrkC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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