WB (Western Blot)
anti-Human, Mouse FOXA2 Antibody | anti-FOXA2 antibody
FOXA2 Antibody
Gene Names
FOXA2; HNF3B; TCF3B
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity purification
Synonyms
FOXA2; N/A; FOXA2 Antibody; HNF3B; TCF3B; Hepatocyte nuclear factor 3-beta; Forkhead box protein A2; Transcription factor 3B; anti-FOXA2 antibody
Reactivity
Human, Mouse
Purity/Purification
Affinity purification
Form/Format
In PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Sequence Length
463
Applicable Applications for anti-FOXA2 antibody
WB (Western Blot)
Immunogen
A synthetic peptide of human FOXA2
Preparation and Storage
Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-FOXA2 antibody
Forkhead box protein A2 (FoxA2, also known as hepatocyte nuclear factor 3beta or HNF3beta) is a transcription factor that plays an important role in hepatocyte function (1). FoxA2/HNF3beta is required for the activation of hepatic gluconeogenic gene expression during fasting (1). Together with the PGC-1beta coactivator, FoxA2/HNF3beta stimulates the expression of genes involved in fatty acid beta-oxidation and therefore increases fatty acid metabolism (2). FoxA2/HNF3beta, along with PGC-1beta, also activates the expression of microsomal triacylglycerol transfer protein (MTP) and promotes VLDL secretion (2). In addition to its roles in metabolic syndromes, FoxA2/HNF3beta is essential for development of the endoderm and midline structures in mouse embryos (3-5).
Product Categories/Family for anti-FOXA2 antibody
References
1. Zhang, L. et al. (2005) Cell Metab 2, 141-8. 2. Wolfrum, C. and Stoffel, M. (2006) Cell Metab 3, 99-110. 3. Levinson-Dushnik, M. and Benvenisty, N. (1997) Mol Cell Biol 17, 3817-22. 4. Weinstein, D.C. et al. (1994) Cell 78, 575-88. 5. Ang, S.L. and Rossant, J. (1994) Cell 78, 561-74.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52kDa
NCBI Official Full Name
hepatocyte nuclear factor 3-beta isoform 1
NCBI Official Synonym Full Names
forkhead box A2
NCBI Official Symbol
FOXA2
NCBI Official Synonym Symbols
HNF3B; TCF3B
NCBI Protein Information
hepatocyte nuclear factor 3-beta
UniProt Protein Name
Hepatocyte nuclear factor 3-beta
UniProt Gene Name
FOXA2
UniProt Synonym Gene Names
HNF3B; TCF3B; HNF-3-beta; HNF-3B; TCF-3B
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Product Notes
The FOXA2 foxa2 (Catalog #AAA266991) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The FOXA2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FOXA2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the FOXA2 foxa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXA2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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