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product-image-AAA76523_AD13.gif Application Data (Image: Confocal image of adult rat cerebellar cortex stained with VSNL1 (green) and chicken polyclonal antibody to MAP2 (red) and DNA (blue). VSNL1 antibody reveals synapses in the molecular layer (ML) strongly. Synaptic regions are also seen in the granule cell layer (GC). The perikarya of Purkinje cells (PC) are revealed with the MAP2 antibody (4). Little staining is seen in the white matter (WM).)

Microtubule associated Protein 2 (MAP2) Antibody | anti-MAP2 antibody

Microtubule associated Protein 2 (MAP2)

Gene Names
MAP2; MAP2A; MAP2B; MAP2C
Reactivity
Human, Mouse, Primate, Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Synonyms
Microtubule associated Protein 2 (MAP2); N/A; anti-MAP2 antibody
Ordering
Reactivity
Human, Mouse, Primate, Rat
Form/Format
Liquid
Sequence Length
1827
Applicable Applications for anti-MAP2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry)
Type Info
Chicken IgY
Immunogen
Recombinant human projection domain sequence, amino acids 377-1505

Application Data

(Image: Confocal image of adult rat cerebellar cortex stained with VSNL1 (green) and chicken polyclonal antibody to MAP2 (red) and DNA (blue). VSNL1 antibody reveals synapses in the molecular layer (ML) strongly. Synaptic regions are also seen in the granule cell layer (GC). The perikarya of Purkinje cells (PC) are revealed with the MAP2 antibody (4). Little staining is seen in the white matter (WM).)

product-image-AAA76523_AD13.gif Application Data (Image: Confocal image of adult rat cerebellar cortex stained with VSNL1 (green) and chicken polyclonal antibody to MAP2 (red) and DNA (blue). VSNL1 antibody reveals synapses in the molecular layer (ML) strongly. Synaptic regions are also seen in the granule cell layer (GC). The perikarya of Purkinje cells (PC) are revealed with the MAP2 antibody (4). Little staining is seen in the white matter (WM).)

Application Data

product-image-AAA76523_AD15.gif Application Data
Related Product Information for anti-MAP2 antibody
Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein tau and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein tau.

Image of primary neuronal culture showing neuronal staining with MAP2 (green) and astrocytes with GFAP (red. Nuclei are counterstained blue.

MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. Antibodies to MAP2 are therefore excellent markers on neuronal cells, their perikarya and neuronal dendrites. In contrast tau is found predominantly in neuronal axons.
Product Categories/Family for anti-MAP2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,954 Da
NCBI Official Full Name
microtubule-associated protein 2 isoform 1
NCBI Official Synonym Full Names
microtubule associated protein 2
NCBI Official Symbol
MAP2
NCBI Official Synonym Symbols
MAP2A; MAP2B; MAP2C
NCBI Protein Information
microtubule-associated protein 2
UniProt Protein Name
Microtubule-associated protein 2
UniProt Gene Name
MAP2
UniProt Synonym Gene Names
MAP-2
UniProt Entry Name
MTAP2_HUMAN

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Product Notes

The MAP2 map2 (Catalog #AAA76523) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Microtubule associated Protein 2 (MAP2) reacts with Human, Mouse, Primate, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Microtubule associated Protein 2 (MAP2) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the MAP2 map2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Microtubule associated Protein 2 (MAP2), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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