Arp2/3 Complex Antibody Sampler Kit | Arp2/3 antibody sampler kit
Arp2/3 Complex
Reactivity
Human, Rat, Mouse
Applications
Immunocytochemistry, Immunoprecipitation, ELISA, Western Blot
Synonyms
Arp2/3 Complex; N/A; Arp2/3 antibody sampler kit
Reactivity
Human, Rat, Mouse
Form/Format
Rabbit polyclonal antibodies are supplied in phosphate-buffered saline (PBS), 50% glycerol, 1mg/ml BSA, and 0.05% sodium azide.
Applicable Applications for Arp2/3 antibody sampler kit
ICC (Immunocytochemistry), IP (Immunoprecipitation), ELISA, WB (Western Blot)
Preparation and Storage
Store at -20 degree C. Stable for 1 year.
Related Product Information for Arp2/3 antibody sampler kit
Background: Cellular morphology, adhesion, and motility occur through dynamic reorganization of actin-based superstructures. Actinbinding proteins are critical for regulating actin polymerization and superstructure formation. The Arp2/3 complex is an actin polymerization-inducing complex that includes Arp2, Arp3, p41-Arc, p34-Arc, p21-Arc, p20-Arc, and p16-Arc. Several nucleation promoting factors, such as WASP and coronin, regulate the activity of the Arp2/3 complex. In addition, the Arp2/3 complex may be regulated by phosphorylation of specific subunits in the complex. Arp2 has two phosphosites, Thr-237 and Thr-238, that are evolutionarily conserved, and are phosphorylated along with Tyr-202 in response to growth factor stimulation. p41-Arc (Arpc1b) subunit Arpc1 has two isoforms in humans, Arpc1a and Arpc1b. PAK1 can bind and phosphorylate Thr-21 in Arpc1b leading to growth factor-stimulated cell motility. In addition, Arpc1b colocalizes with gamma- tubulin at centrosomes and stimulates Aurora A activity.
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Product Notes
The Human, Rat, Mouse Arp2/3 (Catalog #AAA71555) is an Antibody Sampler Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA71555 Antibody Sampler Kit recognizes Human, Rat, Mouse Arp2/3. AAA Biotech's Arp2/3 Complex can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IP (Immunoprecipitation), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the Arp2/3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Arp2/3 Complex, Antibody Sampler Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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