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product-image-AAA76525_AD13.gif Application Data (Image: Western blot of extract of rat brain stem crude extract stained with chicken Neurofilament alpha-internexin/NF66, showing a single strong clean band at ~66kDa. Protocol on datasheet.)

Neurofilament alpha-internexin/NF66 Antibody | anti-NF66 antibody

Neurofilament alpha-internexin/NF66

Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
Neurofilament alpha-internexin/NF66; N/A; anti-NF66 antibody
Ordering
Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Applicable Applications for anti-NF66 antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Type Info
Chicken IgY
Immunogen
recombinant alpha-internexin

Application Data

(Image: Western blot of extract of rat brain stem crude extract stained with chicken Neurofilament alpha-internexin/NF66, showing a single strong clean band at ~66kDa. Protocol on datasheet.)

product-image-AAA76525_AD13.gif Application Data (Image: Western blot of extract of rat brain stem crude extract stained with chicken Neurofilament alpha-internexin/NF66, showing a single strong clean band at ~66kDa. Protocol on datasheet.)

Application Data

(Image: Mixed neuron glia cultures stain with chicken Neurofilament alpha-internexin/NF66 (red) and counterstained with Coronin 1a, (green) which is an excellent marker of microglia and lymphocytes. The chicken internexin antibody is an excellent marker of neuronal processes in these cultures.)

product-image-AAA76525_AD15.gif Application Data (Image: Mixed neuron glia cultures stain with chicken Neurofilament alpha-internexin/NF66 (red) and counterstained with Coronin 1a, (green) which is an excellent marker of microglia and lymphocytes. The chicken internexin antibody is an excellent marker of neuronal processes in these cultures.)
Related Product Information for anti-NF66 antibody
alpha-internexin is a ~66 kDa Class IV intermediate filament originally discovered as it copurifies with other neurofilament subunits. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M anbd NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
Product Categories/Family for anti-NF66 antibody

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Product Notes

The NF66 (Catalog #AAA76525) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Neurofilament alpha-internexin/NF66 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Neurofilament alpha-internexin/NF66 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the NF66 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurofilament alpha-internexin/NF66, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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