Complement C3 Native Protein | C3 native protein
Purified native Human Complement C3 protein
Gene Names
C3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
Purity
>99% pure
Synonyms
Complement C3; N/A; Purified native Human Complement C3 protein; Complement C3, C3 protein, Complement C-3, Complement C 3, Complement C-3 protein, Complement C 3 protein; C3 native protein
Host
Human Plasma
Purity/Purification
>99% pure
Form/Format
Frozen liquid in Sodium Phosphate Buffer, pH 7.2 with 150mM NaCl.
Concentration
1.67mg/ml (varies by lot)
Sequence Length
1663
Species
Human
Protein Type
Native
Contaminants
Shows only one band to C3 molecular weight; ~180KD
Biohazard
Non-reactive for HIV-1/HCV/HBV by NAT, HBsAg, HCV Ab, HIV 1 & 2 Ab, and RPR by currently approved FDA methods. However, handle as though potentially infectious.
Biological Significance
Native human C3 is a naturally glycosylated polypeptide containing two disulfide-linked chains. C3 is central to the activation of all three pathways of complement activation. Initiation of each pathway generates proteolytic enzyme complexes (C3 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in C3 releasing the anaphylatoxin C3a and activating C3b. For a brief time (~60 us) this nascent C3b is capable of reacting with and covalently coupling to hydroxyl groups on the target surface.
Dry Ice Shipment
Extra charge may be applied to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships on dry ice. Upon receipt, store at -20°C.
Product Categories/Family for C3 native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
complement C3 preproprotein
NCBI Official Synonym Full Names
complement C3
NCBI Official Symbol
C3
NCBI Official Synonym Symbols
ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
NCBI Protein Information
complement C3
UniProt Protein Name
Complement C3
UniProt Gene Name
C3
UniProt Synonym Gene Names
CPAMD1; C3bc; ASP
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Product Notes
The C3 c3 (Catalog #AAA224709) is a Native Protein produced from Human Plasma and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Complement C3, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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