Rabbit anti-Mouse ACVR2B Monoclonal Antibody | anti-ACVR2B antibody
Rabbit anti Mouse ACVR2B Monoclonal Antibody
Gene Names
ACVR2B; HTX4; ACTRIIB; ActR-IIB
Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
ACVR2B, Antibody; Rabbit anti Mouse ACVR2B Monoclonal Antibody; 930516B21Rik, ActRIIB; anti-ACVR2B antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Purity/Purification
Protein A
Form/Format
0.2 μm filtered solution in PBS.
Sequence Length
512
Applicable Applications for anti-ACVR2B antibody
ELISA
Immunogen
Recombinant Mouse ACVR2B protein
Preparation and Storage
Store at -20°C, avoid freeze/thaw cycles.
Related Product Information for anti-ACVR2B antibody
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of skeletal muscle growth, is regarded as a potential therapeutic target and binds to ACVR2B effectively, and to a lesser extent, to ACVR2A. The structure of human ACVR2B kinase domain in complex with adenine establishes the conserved bilobal architecture consistent with all other catalytic kinase domains. Haplotype structure at the ACVR2B and follistatin loci may contribute to interindividual variation in skeletal muscle mass and strength. Defects in ACVR2B are a cause of left-right axis malformations.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 61 kDa
NCBI Official Full Name
activin receptor type-2B
NCBI Official Synonym Full Names
activin A receptor type 2B
NCBI Official Symbol
ACVR2B
NCBI Official Synonym Symbols
HTX4; ACTRIIB; ActR-IIB
NCBI Protein Information
activin receptor type-2B
UniProt Protein Name
Activin receptor type-2B
UniProt Gene Name
ACVR2B
UniProt Synonym Gene Names
ACTR-IIB
UniProt Entry Name
AVR2B_HUMAN
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Product Notes
The ACVR2B acvr2b (Catalog #AAA173496) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Mouse ACVR2B Monoclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ACVR2B can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the ACVR2B acvr2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACVR2B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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