Mouse AIPL1 Monoclonal Antibody | anti-AIPL1 antibody

AIPL1 antibody

Cat. Num. AAA74788

• Gene Names: AIPL1; LCA4; AIPL2
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
• Purity: AIPL1 antibody was purified by affinity chromatography.
• Synonyms: AIPL1, Antibody; AIPL1 antibody; Monoclonal AIPL1; Anti-AIPL1; Aryl hydrocarbon receptor interacting protein-like 1; LCA4; AIPL2; AIPL1; AIPL 1; AIPL-1; anti-AIPL1 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 3B4
• Purity/Purification: AIPL1 antibody was purified by affinity chromatography.
• Form/Format: Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 500 ug-1 mg/ml (varies by lot)
• Sequence Length: 384

• Applicable Applications for anti-AIPL1 antibody: WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
• Biological Significance: Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are identified at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA.
• Cross-Reactivity: Human
• Immunogen: AIPL1 antibody was raised in mouse using a full length recombinant protein of human AIPL1 (NP_055151) produced in HEK293T cells, as the immunogen.
• Preparation and Storage: Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

IF (Immunofluorescence)

(Immunofluorescent staining of COS7 cells transiently transfected with recombinant AIPL1 protein using AIPL1 antibody)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of AIPL1 protein in paraffin embedded Carcinoma of Human thyroid tissue using AIPL1 antibody)

WB (Western Blot)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant AIPL1 protein (Right) or empty vector (Left) detected with AIPL1 antibody)

Related Product Information for anti-AIPL1 antibody

Mouse monoclonal AIPL1 antibody

Product Categories/Family for anti-AIPL1 antibody

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 74272276
• NCBI GeneID: 23746
• NCBI Accession #: NP_055151
• NCBI GenBank Nucleotide #: NM_014336.3
• UniProt Accession #: Q9NZN9; Q659W3; Q659W4; Q6ZZB6; Q8N6A0; Q9H873; Q9NS10; D3DTM4
• Molecular Weight: 40,901 Da
• NCBI Official Full Name: aryl-hydrocarbon-interacting protein-like 1 isoform 1
• NCBI Official Synonym Full Names: aryl hydrocarbon receptor interacting protein-like 1
• NCBI Official Symbol: AIPL1
• NCBI Official Synonym Symbols: LCA4; AIPL2
• NCBI Protein Information: aryl-hydrocarbon-interacting protein-like 1
• UniProt Protein Name: Aryl-hydrocarbon-interacting protein-like 1
• UniProt Gene Name: AIPL1
• UniProt Synonym Gene Names: AIPL2
• UniProt Entry Name: AIPL1_HUMAN