IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Angiosarcoma stained with CD31 Monoclonal Antibody (JC/70A))
Mouse Alpha-1-Antitrypsin (SERPINA1) Monoclonal Antibody | anti-SERPINA1 antibody
Alpha-1-Antitrypsin (SERPINA1) (Hepatocellular & Histiocytic Marker)
Gene Names
SERPINA1; PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT
Reactivity
Human. Others not known.
Applications
Immunohistochemistry, Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
Alpha-1-Antitrypsin (SERPINA1), Antibody; Alpha-1-Antitrypsin (SERPINA1) (Hepatocellular & Histiocytic Marker); A1AT; AAT; Alpha 1 antiproteinase Alpha 1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; alpha1 proteinase inhibitor; Alpha1AT; Dom1; Serine (or cysteine) proteinase inhibitor clade A member 1; Serine protease inhibitor 1-1; Serine protease inhibitor A1a; Serpin A1a; Serpin peptidase inhibitor clade A member 1; Serpina1; Short peptide from AAT; SPAAT; Spi1-1; anti-SERPINA1 antibody
Host
Mouse
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG1
Clone Number
AAT/1379
Specificity
The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
418
Applicable Applications for anti-SERPINA1 antibody
IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant human Alpha-1-Antitrypsin (AAT) protein fragment
Cellular Localization
Cytoplasmic
Hu-chromosome Location
14q32.1
Positive Control
HepG2 Cells. Tonsil, Hepatocellular Carcinoma or Histiocytoma.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Angiosarcoma stained with CD31 Monoclonal Antibody (JC/70A))
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Angiosarcoma stained with CD31 Monoclonal Antibody (JC/70A))
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with Alpha-1-Antitrypsin Monoclonal Antibody (AAT/1379))
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with Alpha-1-Antitrypsin Monoclonal Antibody (AAT/1379))
References
Atkinson, G.W., Ann Clin Lab Sci 3:345-352, 1973.Kyaw-Myint, T.O., et al., Clin Chem Acta 59:51-54, 1975.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54kDa
NCBI Official Full Name
alpha-1-antitrypsin
NCBI Official Synonym Full Names
serpin family A member 1
NCBI Official Symbol
SERPINA1
NCBI Official Synonym Symbols
PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT
NCBI Protein Information
alpha-1-antitrypsin
UniProt Protein Name
Alpha-1-antitrypsin
UniProt Gene Name
SERPINA1
UniProt Synonym Gene Names
AAT; PI; SPAAT
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Product Notes
The SERPINA1 serpina1 (Catalog #AAA214477) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Alpha-1-Antitrypsin (SERPINA1) (Hepatocellular & Histiocytic Marker) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's Alpha-1-Antitrypsin (SERPINA1) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the SERPINA1 serpina1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha-1-Antitrypsin (SERPINA1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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