Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-bcl6
Form/Format
Bcl-6 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
Control
Tonsil, Lymph Node
Localization
Nuclear
Reactivity Note
Paraffin, Frozen
Preparation and Storage
Store at 2 to 8 degree C in the dark.
Related Product Information for anti-bcl-6 antibody
bcl-6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein. Antibodies to this protein stain the germinal center cells in lymphoid follicles, follicular cells and interfollicular cells in Follicular Lymphoma, Diffuse Large B-Cell Lymphomas, Burkitt's Lymphoma, and the majority of the Reed-Sternberg cells in Nodular Lymphocyte-Predominant Hodgkin's Disease.Bcl-6 is also useful in identifying neoplastic cells in cases of nodular Lymphocyte-Predominant Hodgkin's Disease. In contrast, anti-bcl-6 rarely stains Mantle-Cell Lymphoma and MALT Lymphoma. bcl-6 expression is seen in approximately 45% of CD30+ Anaplastic Large-Cell Lymphomas but is consistently absent in other peripheral T-cell Lymphomas.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78,846 Da
NCBI Official Full Name
B-cell lymphoma 6 protein isoform 2
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 6
NCBI Official Symbol
BCL6
NCBI Official Synonym Symbols
BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
NCBI Protein Information
B-cell lymphoma 6 protein; BCL-5; BCL-6; protein LAZ-3; OTTHUMP00000209895; OTTHUMP00000209897; OTTHUMP00000209900; zinc finger protein 51; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein transcript; zinc finger transcription factor BCL6S; cys-his2 zinc finger transcription factor; zinc finger and BTB domain-containing protein 27; lymphoma-associated zinc finger gene on chromosome 3
UniProt Protein Name
B-cell lymphoma 6 protein
UniProt Gene Name
BCL6
UniProt Synonym Gene Names
BCL5; LAZ3; ZBTB27; ZNF51
UniProt Entry Name
BCL6_HUMAN
Similar Products
Product Notes
The bcl-6 bcl6 (Catalog #AAA59172) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The bcl-6 RMab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "bcl-6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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