WB (Western Blot)
(Western Blot of HepG2 Cell Lysate using Bcl-10 Monoclonal Antibody (BL10/411))
Mouse anti-Human BCL10 Monoclonal Antibody | anti-BCL10 antibody
BCL10 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody
Gene Names
BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
BCL10, Antibody; BCL10 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody; B-cell CLL/lymphoma 10, B-cell leukemia/lymphoma 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, caspase-recruiting domain-containing protein, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, Cellular-E10 (cE10), CIPER, hCLAP, mE10, R-RCD1; anti-BCL10 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
BL10/411
Specificity
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF-kB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
233
Applicable Applications for anti-BCL10 antibody
IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Cellular Localization
Nuclear and Cytoplasmic
Immunogen
Human BCL10 recombinant protein (epitope aa122-168)
Hu-Chromosome Location
1p22.3
Positive Control
HepG2 cells or Lymphoma.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
WB (Western Blot)
(Western Blot of HepG2 Cell Lysate using Bcl-10 Monoclonal Antibody (BL10/411))
WB (Western Blot)
(Western Blot of HepG2 Cell Lysate using Bcl-10 Monoclonal Antibody (BL10/411))
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with BCL10 Monoclonal Antibody (BL10/411).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with BCL10 Monoclonal Antibody (BL10/411).)
References
Ye H et. al. Am J Pathol 2000;157:1147-54
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33kDa
NCBI Official Full Name
B-cell lymphoma/leukemia 10 isoform 1
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 10
NCBI Official Symbol
BCL10
NCBI Official Synonym Symbols
CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
NCBI Protein Information
B-cell lymphoma/leukemia 10
UniProt Protein Name
B-cell lymphoma/leukemia 10
UniProt Gene Name
BCL10
UniProt Synonym Gene Names
CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10
UniProt Entry Name
BCL10_HUMAN
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Product Notes
The BCL10 bcl10 (Catalog #AAA62501) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BCL10 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's BCL10 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the BCL10 bcl10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL10, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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