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FCM/FACS (Flow Cytometry)
(BCL10 Antibody (N-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit BCL10 Polyclonal Antibody | anti-BCL10 antibody
BCL10 Antibody (N-term)
Gene Names
BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
BCL10, Antibody; BCL10 Antibody (N-term); B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10; BCL10; CLAP; anti-BCL10 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This BCL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human BCL10.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
24-51
Sequence Length
233
Applicable Applications for anti-BCL10 antibody
FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(BCL10 Antibody (N-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(BCL10 Antibody (N-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of BCL10 Antibody (N-term) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of BCL10 Antibody (N-term) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
IHC (Immunohiostchemistry)
(BCL10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the BCL10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(BCL10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the BCL10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(BCL10 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the BCL10 antibody detected the BCL10 protein (arrow).)
WB (Western Blot)
(BCL10 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the BCL10 antibody detected the BCL10 protein (arrow).)
Related Product Information for anti-BCL10 antibody
This gene was identified by its translocation in a case of
mucosa-associated lymphoid tissue (MALT) lymphoma. The protein
encoded by this gene contains a caspase recruitment domain (CARD),
and has been shown to induce apoptosis and to activate NF-kappaB.
This protein is reported to interact with other CARD domain
containing proteins including CARD9, 10, 11 and 14, which are
thought to function as upstream regulators in NF-kappaB signaling.
This protein is found to form a complex with MALT1, a protein
encoded by another gene known to be translocated in MALT lymphoma.
MALT1 and this protein are thought to synergize in the activation
of NF-kappaB, and the deregulation of either of them may contribute
to the same pathogenetic process that leads to the malignancy.
mucosa-associated lymphoid tissue (MALT) lymphoma. The protein
encoded by this gene contains a caspase recruitment domain (CARD),
and has been shown to induce apoptosis and to activate NF-kappaB.
This protein is reported to interact with other CARD domain
containing proteins including CARD9, 10, 11 and 14, which are
thought to function as upstream regulators in NF-kappaB signaling.
This protein is found to form a complex with MALT1, a protein
encoded by another gene known to be translocated in MALT lymphoma.
MALT1 and this protein are thought to synergize in the activation
of NF-kappaB, and the deregulation of either of them may contribute
to the same pathogenetic process that leads to the malignancy.
Product Categories/Family for anti-BCL10 antibody
References
Bhattacharyya, S., et al. Exp. Cell Res. 316(19):3317-3327(2010)
Edin, S., et al. Mol. Immunol. 47 (11-12), 2057-2064 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Bhattacharyya, S., et al. J. Biol. Chem. 285(1):522-530(2010)
Rehman, A.O., et al. Int J Oral Sci 1(3):105-118(2009)
Edin, S., et al. Mol. Immunol. 47 (11-12), 2057-2064 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Bhattacharyya, S., et al. J. Biol. Chem. 285(1):522-530(2010)
Rehman, A.O., et al. Int J Oral Sci 1(3):105-118(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26252
NCBI Official Full Name
B-cell lymphoma/leukemia 10
NCBI Official Synonym Full Names
B-cell CLL/lymphoma 10
NCBI Official Symbol
BCL10
NCBI Official Synonym Symbols
CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
NCBI Protein Information
B-cell lymphoma/leukemia 10
UniProt Protein Name
B-cell lymphoma/leukemia 10
UniProt Gene Name
BCL10
UniProt Synonym Gene Names
CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10
UniProt Entry Name
BCL10_HUMAN
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Product Notes
The BCL10 bcl10 (Catalog #AAA286035) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-51. The BCL10 Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's BCL10 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BCL10 bcl10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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