Mouse anti-Human BCL10 Monoclonal Antibody | anti-BCL10 antibody

BCL10 (MALT-Lymphoma Marker)

Cat. Num. AAA215362

• Gene Names: BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
• Reactivity: Human
• Applications: Immunohistochemistry, Flow Cytometry, Functional Assay
• Purity: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: BCL10, Antibody; BCL10 (MALT-Lymphoma Marker); B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; caspase-recruiting domain-containing protein; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN; Cellular-E10 (cE10); CIPER; hCLAP; mE10; R-RCD1; anti-BCL10 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: rBL10/411
• Specificity: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

• Applicable Applications for anti-BCL10 antibody: IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
• Immunogen: Human BCL10 recombinant protein (epitope aa122-168)
• Cellular Localization: Nuclear and Cytoplasmic
• Antibody Type: Recombinant Antibody
• Hu-chromosome Location: 1p22.3
• Positive Control: K562 or HepG2 cells. Human Lymphoma.
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C.; Antibody without azide: store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

FCM/FACS (Flow Cytometry)

(Flow Cytometric Analysis of PFA-fixed K562 cells using BCL10 Recombinant Mouse Monoclonal Antibody (rBL10/411) followed by Goat anti-mouse IgG-CF488 (Blue); Isotype Control (Red),)

SDS-PAGE

(SDS-PAGE Analysis Purified BCL10 Recombinant Mouse Monoclonal Antibody (rBL10/411). Confirmation of Purity and Integrity of Antibody.)

References

Ye H et. al. Am J Pathol 2000;157:1147-54.

NCBI and Uniprot Product Information

• NCBI GeneID: 8915
• UniProt Accession #: O95999
• Molecular Weight: 33kDa
• NCBI Official Synonym Full Names: BCL10 immune signaling adaptor
• NCBI Official Symbol: BCL10
• NCBI Official Synonym Symbols: CLAP; mE10; CIPER; IMD37; c-E10; CARMEN
• NCBI Protein Information: B-cell lymphoma/leukemia 10
• UniProt Protein Name: B-cell lymphoma/leukemia 10
• UniProt Gene Name: BCL10
• UniProt Synonym Gene Names: CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10
• UniProt Entry Name: BCL10_HUMAN