IF (Immunofluorescence)
(Immunofluorescence of cIAP1(green) in Hela cells using cIAP1 Rabbit mAb at dilution 1/200, and DAPI(blue))
anti-Human c IAP1 Monoclonal Antibody | anti-cIAP1 antibody
c IAP1 Rabbit mAb
Gene Names
BIRC2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Affinity Purified
Synonyms
c IAP1, Antibody; c IAP1 Rabbit mAb; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; anti-cIAP1 antibody
Host
Recombinant Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
S01-1C5
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-cIAP1 antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
A synthetic peptide of human cIAP1
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence of cIAP1(green) in Hela cells using cIAP1 Rabbit mAb at dilution 1/200, and DAPI(blue))
IF (Immunofluorescence)
(Immunofluorescence of cIAP1(green) in Hela cells using cIAP1 Rabbit mAb at dilution 1/200, and DAPI(blue))
WB (Western Blot)
(Western blot detection of c-IAP1 in K562 cell lysates using c-IAP1 Rabbit mAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:70kDa.)
WB (Western Blot)
(Western blot detection of c-IAP1 in K562 cell lysates using c-IAP1 Rabbit mAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:70kDa.)
Related Product Information for anti-cIAP1 antibody
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling, and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, TRAF2, DIABLO/SMAC, MAP3K14/NIK, MAP3K5/ASK1, IKBKG/NEMO, IKBKE and MXD1/MAD1. Can also function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway, targeting effector caspases for neddylation and inactivation. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8. Can stimulate the transcriptional activity of E2F1. Plays a role in the modulation of the cell cycle.
Product Categories/Family for anti-cIAP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
618
NCBI Official Full Name
baculoviral IAP repeat-containing protein 2 isoform 1
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 2
NCBI Official Symbol
BIRC2
NCBI Official Synonym Symbols
API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1
NCBI Protein Information
baculoviral IAP repeat-containing protein 2; IAP-2; IAP homolog B; apoptosis inhibitor 1; RING finger protein 48; inhibitor of apoptosis protein 2; baculoviral IAP repeat-containing 2; NFR2-TRAF signalling complex protein; TNFR2-TRAF-signaling complex pro
UniProt Protein Name
Baculoviral IAP repeat-containing protein 2
UniProt Gene Name
BIRC2
UniProt Synonym Gene Names
API1; IAP2; MIHB; RNF48; IAP-2; hIAP-2; hIAP2
UniProt Entry Name
BIRC2_HUMAN
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Product Notes
The cIAP1 birc2 (Catalog #AAA314333) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The c IAP1 Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's c IAP1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the cIAP1 birc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "c IAP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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