Mouse anti-Human CD105 Monoclonal Antibody | anti-CD105 antibody

CD105 Monoclonal Antibody

Cat. Num. AAA319986

• Gene Names: ENG; END; ORW; HHT1; ORW1; CD105
• Reactivity: Human
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: CD105, Antibody; CD105 Monoclonal Antibody; Endoglin; ENG; END; CD antigen CD105; anti-CD105 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Specificity: CD105 Monoclonal Antibody detects endogenous levels of CD105 protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-CD105 antibody: ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human CD105 expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

Application Data

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of HepG2 cells using CD105 Monoclonal Antibody (green) and negative control (purple).)

IF (Immunofluorescence)

(Immunofluorescence analysis of HepG2 cells using CD105 Monoclonal Antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded kidney cancer tissues (left) and stomach cancer tissues (right) with DAB staining using CD105 Monoclonal Antibody.)

WB (Western Blot)

(Western Blot analysis using CD105 Monoclonal Antibody against HEK293 (1) and CD105-hIgGFc transfected HEK293 (2) cell lysate.)

Related Product Information for anti-CD105 antibody

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Product Categories/Family for anti-CD105 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 4557555
• NCBI GeneID: 2022
• NCBI Accession #: NP_000109.1
• NCBI GenBank Nucleotide #: NM_000118.2
• UniProt Accession #: P17813; Q14248; Q14926; Q5T9C0
• Molecular Weight: 70,578 Da
• NCBI Official Full Name: endoglin isoform 2
• NCBI Official Synonym Full Names: endoglin
• NCBI Official Symbol: ENG
• NCBI Official Synonym Symbols: END; ORW; HHT1; ORW1; CD105
• NCBI Protein Information: endoglin; CD105 antigen
• UniProt Protein Name: Endoglin
• UniProt Gene Name: ENG
• UniProt Synonym Gene Names: END
• UniProt Entry Name: EGLN_HUMAN