Rat anti-Human, Dog CD132 Monoclonal Antibody | anti-CD132 antibody
Anti-Hu CD132 Purified
Gene Names
IL2RG; P64; CIDX; IMD4; CD132; SCIDX; IL-2RG; SCIDX1
Reactivity
Human, Dog
Applications
Flow Cytometry, Functional Assay
Purity
Purified by Protein-G Affinity Chromatography
Synonyms
CD132, Antibody; Anti-Hu CD132 Purified; interleukin 2 receptor subunit gamma; common gamma chain; interleukin 2 receptor gamma; IL2RG; SCIDX; IMD4; anti-CD132 antibody
Host
Rat
Reactivity
Human, Dog
Clonality
Monoclonal
Isotype
IgG2b kappa
Clone Number
TUGh4
Specificity
The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.
Purity/Purification
Purified by Protein-G Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
369
Applicable Applications for anti-CD132 antibody
FCM/FACS (Flow Cytometry)
Immunogen
Human CD132-transfected cell line
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-CD132 antibody
CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Cytokine receptor common subunit gamma
NCBI Official Synonym Full Names
interleukin 2 receptor subunit gamma
NCBI Official Symbol
IL2RG
NCBI Official Synonym Symbols
P64; CIDX; IMD4; CD132; SCIDX; IL-2RG; SCIDX1
NCBI Protein Information
cytokine receptor common subunit gamma
UniProt Protein Name
Cytokine receptor common subunit gamma
UniProt Gene Name
IL2RG
UniProt Synonym Gene Names
IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG
UniProt Entry Name
IL2RG_HUMAN
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Product Notes
The CD132 il2rg (Catalog #AAA129006) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Hu CD132 Purified reacts with Human, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's CD132 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD132 il2rg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD132, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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