IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human papillary renal cell carcinoma stained with CD133/Prominin Mouse Monoclonal Antibody (PROM/6316).)
Mouse anti-Human CD133/Prominin Monoclonal Antibody | anti-PROM1 antibody
CD133/Prominin (Cancer Stem Cell Marker) Mouse Monoclonal Antibody [Clone PROM/6316]
Gene Names
PROM1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
CD133/Prominin, Antibody; CD133/Prominin (Cancer Stem Cell Marker) Mouse Monoclonal Antibody [Clone PROM/6316]; CD133/Prominin (Cancer Stem Cell Marker); Antigen AC133; CORD12; Hematopoietic stem cell antigen; hProminin; MCDR2; PROM1; Prominin like protein 1 precursor; PROML1; RP41; STGD4; anti-PROM1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG1
Clone Number
PROM/6316
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-PROM1 antibody
IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant chimericPROM1 protein (around aa180-380 and aa612-765). This Mab recognizes both glycosylated and non-glycosylated extracellular domains of CD133.
Cellular Localization
Apical cell membrane, Endoplasmic reticulum, Endoplasmic reticulum-Golgi intermediate compartment
Positive Control
Raji, HeLa or SW480 cells. Human tonsil.
Hu-chromosome Location
4p15.32
Unigene
614734
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human papillary renal cell carcinoma stained with CD133/Prominin Mouse Monoclonal Antibody (PROM/6316).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human papillary renal cell carcinoma stained with CD133/Prominin Mouse Monoclonal Antibody (PROM/6316).)
Related Product Information for anti-PROM1 antibody
CD133, also known as PROML1 or Prominin, is a stem cell antigen that may be useful for the selection and expansion of hematopoietic cells and may be used as a positive marker for the characterization of trophoblast cell lines. The human CD133 gene maps to chromosome 4p15. 32 and encodes an 865 amino acid protein. The CD133 gene codes for a pentaspantransmembrane glycoprotein that is expressed on primitive hematopoietic stem, progenitor, retinoblastoma, hemangioblasts and neural stem cells and developing epithelium. The 5-TM structure includes an extracellular N-terminus, two short intra- cellular loops, two large extracellular loops and an intracellular C-terminus. CD133 is a candidate gene for retinal proteins that are targeted to plasma membrane protrusions. These retinal proteins, including CD133, may influence the shedding of photoreceptive membranes from the terminal end of the outer segments of vertebrate photoreceptors, where they are phagocytosed by the retinal pigment epithelium, and represent candidates for inherited retinal degenerations.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
97kDa
NCBI Official Full Name
Prominin-1
NCBI Official Synonym Full Names
prominin 1
NCBI Official Symbol
PROM1
NCBI Official Synonym Symbols
RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
NCBI Protein Information
prominin-1; hProminin; antigen AC133; prominin-like protein 1; hematopoietic stem cell antigen
UniProt Protein Name
Prominin-1
UniProt Gene Name
PROM1
UniProt Synonym Gene Names
PROML1
UniProt Entry Name
PROM1_HUMAN
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Product Notes
The PROM1 prom1 (Catalog #AAA216023) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD133/Prominin (Cancer Stem Cell Marker) Mouse Monoclonal Antibody [Clone PROM/6316] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD133/Prominin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the PROM1 prom1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD133/Prominin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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