SDS-PAGE
(SDS-PAGE Analysis Purified CD33 Mouse Monoclonal Antibody (SIGLEC3/3600). Confirmation of Integrity and Purity of Antibody.)
Mouse anti-Human CD33/SIGLEC3 Monoclonal Antibody | anti-CD33 antibody
CD33/SIGLEC3 (Myeloid Cell Surface Antigen) Mouse Monoclonal Antibody [Clone SIGLEC3/3600]
Gene Names
CD33; p67; SIGLEC3; SIGLEC-3
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
CD33/SIGLEC3, Antibody; CD33/SIGLEC3 (Myeloid Cell Surface Antigen) Mouse Monoclonal Antibody [Clone SIGLEC3/3600]; CD33/SIGLEC3 (Myeloid Cell Surface Antigen); gp67; My9; Myeloid cell surface antigen CD33; p67; Sialic acid-binding Ig-like lectin 3 (SIGLEC3); anti-CD33 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2c, kappa
Clone Number
SIGLEC3/3600
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CD33 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment (around aa51-224) of human CD33 protein (exact sequence is proprietary)
Cellular Localization
Cell surface
Positive Control
Human dendritic and mast cells. Human lymph nodes and tonsils.
Hu-chromosome Location
19q13.33
Unigene
83731
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified CD33 Mouse Monoclonal Antibody (SIGLEC3/3600). Confirmation of Integrity and Purity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified CD33 Mouse Monoclonal Antibody (SIGLEC3/3600). Confirmation of Integrity and Purity of Antibody.)
Related Product Information for anti-CD33 antibody
Recognizes a 67kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Calculated MW: 25kDa/33kDa/39kDa
Observed MW: 77kDa
Observed MW: 77kDa
NCBI Official Full Name
Myeloid cell surface antigen CD33
NCBI Official Synonym Full Names
CD33 molecule
NCBI Official Symbol
CD33
NCBI Official Synonym Symbols
p67; SIGLEC3; SIGLEC-3
NCBI Protein Information
myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3
UniProt Protein Name
Myeloid cell surface antigen CD33
UniProt Gene Name
CD33
UniProt Synonym Gene Names
SIGLEC3; Siglec-3
UniProt Entry Name
CD33_HUMAN
Similar Products
Product Notes
The CD33 cd33 (Catalog #AAA216063) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD33/SIGLEC3 (Myeloid Cell Surface Antigen) Mouse Monoclonal Antibody [Clone SIGLEC3/3600] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD33/SIGLEC3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD33 cd33 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD33/SIGLEC3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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