Mouse CD36 Monoclonal Antibody | anti-CD36 antibody

CD36 (Platelet & Microvessel Marker) Mouse Monoclonal Antibody

Cat. Num. AAA62878

• Gene Names: CD36; FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10
• Reactivity: Human; Others not known.
• Applications: Immunofluorescence, Flow Cytometry, Functional Assay, Functional Assay
• Synonyms: CD36, Antibody; CD36 (Platelet & Microvessel Marker) Mouse Monoclonal Antibody; Adipocyte membrane protein; CHDS7; Collagen receptor, platelet; fatty acid translocase (FAT); Fatty acid transport protein; glycoprotein iiib (GP IIIb); PAS IV; PAS-4; pas4 protein; platelet collagen receptor; Platelet glycoprotein 4; scarb3; Scavenger receptor class B member 3; thrombospondin receptor; anti-CD36 antibody

• Host: Mouse
• Reactivity: Human; Others not known.
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: 1E8
• Specificity: Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 472

• Applicable Applications for anti-CD36 antibody: IF (Immunofluorescence), FCM/FACS (Flow Cytometry), FA (Functional Assay)
• Cellular Localization: Cell Surface
• Immunogen: Human CD36 from platelets
• Human Chromosome Location: 7q11.2
• Positive Control: HEL or U937 cells. Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil.
• Preparation and Storage: Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified CD36 Mouse Monoclonal Antibody (1E8).Confirmation of Purity and Integrity of Antibody.)

References

Stomski FC; Gani JS; Bates RC; Burns GF. Adhesion to thrombospondin by human embryonic fibroblasts is mediated by multiple receptors and includes a role for glycoprotein 88 (CD36). Experimental Cell Research, 1992, 198(1):85-92. Biggs BA; Gooze L; Wycherley K; Wilkinson D; Boyd AW; Forsyth KP; Edelman L; Brown GV; Leech JH. Knob-independent cytoadherence of Plasmodium falciparum to the leukocyte differentiation antigen CD36. Journal of Experimental Medicine, 1990, 171(6):1883-92

NCBI and Uniprot Product Information

• NCBI GI #: 48375178
• NCBI GeneID: 948
• NCBI Accession #: NP_000063.2
• NCBI GenBank Nucleotide #: NM_000072.3
• UniProt Accession #: P16671; Q13966; Q16093; Q8TCV7; Q9BPZ8; Q9BQC2; Q9BZM8; Q9BZN3; D9IX66; D9IX67; D9IX68; D9IX69
• Molecular Weight: 80-90kDa
• NCBI Official Full Name: platelet glycoprotein 4 isoform 1
• NCBI Official Synonym Full Names: CD36 molecule
• NCBI Official Symbol: CD36
• NCBI Official Synonym Symbols: FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10
• NCBI Protein Information: platelet glycoprotein 4
• UniProt Protein Name: Platelet glycoprotein 4
• UniProt Gene Name: CD36
• UniProt Synonym Gene Names: GP3B; GP4; FAT; GPIIIB; GPIV
• UniProt Entry Name: CD36_HUMAN