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product-image-AAA76651_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry staining of MO47025 on human pancreas tissue.)

Mouse anti-Human CD45/LCA (Leukocyte Common Antigen) Monoclonal Antibody | anti-CD45/LCA antibody

CD45/LCA (Leukocyte Common Antigen)

Gene Names
PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
CD45/LCA (Leukocyte Common Antigen), Antibody; CD45/LCA (Leukocyte Common Antigen); anti-CD45/LCA antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG
Form/Format
Affinity Purified antibody
Liquid with PBS buffer, pH7.4 with 0.02% Sodium Azide
Applicable Applications for anti-CD45/LCA antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant Human CD45/LCA
Preparation and Storage
The product can be stored undiluted for several weeks at 4 degree C. Dilute only immediately before use. Aliquot and store at -20 degree C for long term. Avoid freeze thaw-cycles.

IHC (Immunohiostchemistry)

(Immunohistochemistry staining of MO47025 on human pancreas tissue.)

product-image-AAA76651_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry staining of MO47025 on human pancreas tissue.)

IHC (Immunohistochemistry)

(Immunohistochemistry staining of MO47025 on human spleen tissue.)

product-image-AAA76651_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry staining of MO47025 on human spleen tissue.)
Related Product Information for anti-CD45/LCA antibody
Anti-CD45 (LCA) Antibody is designed to detect CD45/LCA (leukocyte common antigen). CD45 is expressed in mostnucleated cells from hematopoietic origin and is essential to regulate T and B cell antigen receptor signalling. Cluster of differentiation 45 (CD45), otherwise known as leukocyte common antigen (LCA), is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family control various cellular processes including: cell growth, oncogenic transformation, and cell differentiation. CD45 is a signalling molecule that is an essential regulator of T and B cell antigen receptor signalling. Anti-CD45 is a biomarker for the majority of lymphoid neoplasms and positively stains most nucleated cells of hematopoietic tissue origin. Certain types of neoplasms, such as Hodgkin's lymphoma and some leukemias lack CD45 meaning that an absence of CD45 does not preclude the presence of lymphoid tumours.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
147,254 Da
NCBI Official Full Name
receptor-type tyrosine-protein phosphatase C isoform 1
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, C
NCBI Official Symbol
PTPRC
NCBI Official Synonym Symbols
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
NCBI Protein Information
receptor-type tyrosine-protein phosphatase C; CD45 antigen; T200 glycoprotein; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase C
UniProt Gene Name
PTPRC
UniProt Synonym Gene Names
CD45; L-CA
UniProt Entry Name
PTPRC_HUMAN

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Product Notes

The CD45/LCA ptprc (Catalog #AAA76651) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD45/LCA (Leukocyte Common Antigen) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD45/LCA (Leukocyte Common Antigen) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD45/LCA ptprc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD45/LCA (Leukocyte Common Antigen), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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