Application Data
(Human peripheral blood lymphocytes and monocytes were stained with Mouse Anti-Human CD74-UNLB followed by Goat Anti-Mouse IgG1, Human ads-PE)
Mouse anti-Human CD74 Monoclonal Antibody | anti-CD74 antibody
Mouse Anti-Human CD74-UNLB
Gene Names
CD74; II; DHLAG; HLADG; Ia-GAMMA
Reactivity
Human
Applications
Immunoprecipitation, Immunohistochemistry, Flow Cytometry, Functional Assay
Synonyms
CD74, Antibody; Mouse Anti-Human CD74-UNLB; Mouse Anti-Human CD74 - Purified, Unlabeled Antibody; Mouse Anti-Human CD74; anti-CD74 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse (BALB/c) IgG1k
Clone Number
LN2
Specificity
Human CD74; Mr 41, 35, 33 kDa
Form/Format
The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Sequence Length
296
Applicable Applications for anti-CD74 antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
Immunogen
Cell line SU-DHL-4 nuclei
Preparation and Storage
Store at 2-8 degree C.
Application Data
(Human peripheral blood lymphocytes and monocytes were stained with Mouse Anti-Human CD74-UNLB followed by Goat Anti-Mouse IgG1, Human ads-PE)
Application Data
(Human peripheral blood lymphocytes and monocytes were stained with Mouse Anti-Human CD74-UNLB followed by Goat Anti-Mouse IgG1, Human ads-PE)
Related Product Information for anti-CD74 antibody
CD74 represents a type II integral membrane protein known as MHC Class II-associated invariant chain (Mr 43, 41, 35, 33 kDa). It is moderately expressed on B cells, and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of Class II molecules on the cell surface
References
1. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford.
2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD74 Section, Academic Press, New York, p. 327.
3. Lamb, C.A., J.W. Yewdell, J.R. Bennink, and P. Cresswell. 1991. Proc. Natl. Acad. Sci. USA 88:5998.
4. Viville, S., J. Neefjes, V. Lotteau, A. Dierich, M. Lemeur, H. Ploegh, C. Benoist, and D. Mathis. 1993. Cell 72:635.
2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD74 Section, Academic Press, New York, p. 327.
3. Lamb, C.A., J.W. Yewdell, J.R. Bennink, and P. Cresswell. 1991. Proc. Natl. Acad. Sci. USA 88:5998.
4. Viville, S., J. Neefjes, V. Lotteau, A. Dierich, M. Lemeur, H. Ploegh, C. Benoist, and D. Mathis. 1993. Cell 72:635.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), isoform CRA_c
NCBI Official Synonym Full Names
CD74 molecule, major histocompatibility complex, class II invariant chain
NCBI Official Symbol
CD74
NCBI Official Synonym Symbols
II; DHLAG; HLADG; Ia-GAMMA
NCBI Protein Information
HLA class II histocompatibility antigen gamma chain; p33; HLA-DR-gamma; OTTHUMP00000224283; OTTHUMP00000224284; OTTHUMP00000224285; OTTHUMP00000224286; OTTHUMP00000224288; OTTHUMP00000224338; MHC HLA-DR gamma chain; Ia-associated invariant chain; gamma chain of class II antigens; HLA-DR antigens-associated invariant chain; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
UniProt Protein Name
HLA class II histocompatibility antigen gamma chain
UniProt Gene Name
CD74
UniProt Synonym Gene Names
DHLAG
UniProt Entry Name
HG2A_HUMAN
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Product Notes
The CD74 cd74 (Catalog #AAA78759) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human CD74-UNLB reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD74 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the CD74 cd74 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD74, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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