Mouse anti-Human, Mouse CDK2 Monoclonal Antibody | anti-CDK2 antibody

Anti-CDK2 Mouse mAb

Cat. Num. AAA14114

• Gene Names: CDK2; CDKN2; p33(CDK2)
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Functional Assay
• Synonyms: CDK2, Antibody; Anti-CDK2 Mouse mAb; p33; anti-CDK2 antibody

• Host: Mouse
• Reactivity: Human, Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 1A6
• Form/Format: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
• Sequence Length: 298

• Applicable Applications for anti-CDK2 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
• Immunogen: Purified recombinant fragment of human CDK2 expressed in E Coli.

IHC (Immunohistchemistry)

(Immunohistochemical analysis of paraffin-embedded colon cancer tissues using CDK2 mouse mAb with DAB staining.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CDK2 mouse mAb with DAB staining.)

FCM (Flow Cytometry)

(Flow cytometric analysis of Jurkat cells using CDK2 mouse mAb (green) and negative control (red).)

IF (Immunofluorescence)

(Immunofluorescence analysis of HeLa cells using CDK2 mouse mAb (green). Red)

WB (Western Blot)

(Western blot analysis using CDK2 mouse mAb against Jurkat (1), HL-60 (2), K562 (3), A431 (4), HeLa (5), and NIH3T3 (6) cell lysate.)

WB (Western Blot)

(Western blot analysis using CDK2 mAb against human CDK2 (AA)

Related Product Information for anti-CDK2 antibody

Entrez Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

NCBI and Uniprot Product Information

• NCBI GI #: 16936528
• NCBI GeneID: 1017
• NCBI Accession #: NP_001789.2
• NCBI GenBank Nucleotide #: NM_001798.4
• UniProt Accession #: P24941; O75100; A8K7C6
• Molecular Weight: 33.9
• NCBI Official Full Name: cyclin-dependent kinase 2 isoform 1
• NCBI Official Synonym Full Names: cyclin dependent kinase 2
• NCBI Official Symbol: CDK2
• NCBI Official Synonym Symbols: CDKN2; p33(CDK2)
• NCBI Protein Information: cyclin-dependent kinase 2
• UniProt Protein Name: Cyclin-dependent kinase 2
• UniProt Gene Name: CDK2
• UniProt Synonym Gene Names: CDKN2