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product-image-AAA59404_IHC13.jpg IHC (Immunohiostchemistry) (Cytokeratin 14 Antibody Immunohistochemistry on an FFPE Cervical Cancer Tissue)

Rabbit anti-Human Cytokeratin 14 Monoclonal Antibody

Cytokeratin 14 (RM328)

Reactivity
Human
Synonyms
Cytokeratin 14, Antibody; Cytokeratin 14 (RM328); keratin 14; KRT14; anti-Cytokeratin 14; anti Cytokeratin 14; anti-KRT14; anti KRT14; anti-Keratin 14; anti Keratin 14; CK 14; CK14; anti-ck14; anti ck14; anti-ck 14; cytokeratin 14; EBS3; EBS4; K14; keratin 14 epidermolysis bullosa simplex Dowling Meara Koebner; Keratin type I cytoskeletal 14; NFJ; anti-Cytokeratin 14 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RM328
Form/Format
Paraffin, Frozen
Cytokeratin 14 RMab is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative
Immunogen
A peptide corresponding to C-terminus of human Cytokeratin-14
Control
Squamous Mucosa, Prostate, Breast, Tonsil, Salivary Gland, Skin, Cervix Carcinoma, Squamous Carcinoma
Localization
Cytoplasmic
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)

IHC (Immunohiostchemistry)

(Cytokeratin 14 Antibody Immunohistochemistry on an FFPE Cervical Cancer Tissue)

product-image-AAA59404_IHC13.jpg IHC (Immunohiostchemistry) (Cytokeratin 14 Antibody Immunohistochemistry on an FFPE Cervical Cancer Tissue)

Dilution Info

product-image-AAA59404_DILUTION15.jpg Dilution Info
Related Product Information for anti-Cytokeratin 14 antibody
Cytokeratin 14 is a Type I polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. It is usually found as a heterotetramer with two cytokeratin 5 molecules, and a Type II keratin. Together, they form the cytoskeleton of epithelial cells. Mutations in the genes for these cytokeratins are associated with Epidermolysis Bullosa Simplex.
Cytokeratin 14 antibody has been studied as a prognostic marker in Breast Cancer. This antibody labels the basal layer of stratifying squamous and non-squamous epithelia. The staining pattern is cytoplasmic. It recognizes Basal Cell Carcinomas and Squamous Cell Carcinomas. Cytokeratin 14 antibody has been demonstrated to be useful in differentiating Squamous Cell Carcinomas from other epithelial tumors. This antibody has also been useful in separating oncocytic tumors of the kidney from renal mimics, as well as in determining metaplastic Carcinomas of the Breast.

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Product Notes

The Cytokeratin 14 (Catalog #AAA59404) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 14 (RM328) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Cytokeratin 14, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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