ICC (Immunocytochemistry)
(ICC staining Cytokeratin 6 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit anti-Human Cytokeratin 6 Monoclonal Antibody | anti-KRT6A antibody
Cytokeratin 6 Antibody
Gene Names
KRT6A; K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; KRT6C; KRT6D
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
Cytokeratin 6, Antibody; Cytokeratin 6 Antibody; CK 6A antibody; CK 6B antibody; CK 6C antibody; CK 6D antibody; CK 6E antibody; CK-6C antibody; CK-6E antibody; Cytokeratin 6a antibody; Cytokeratin 6B antibody; Cytokeratin 6C antibody; Cytokeratin 6D antibody; Cytokeratin 6E antibody; Cytokeratin-6C antibody; Cytokeratin-6E antibody; K2C6C_HUMAN antibody; K6a keratin antibody; K6b keratin antibody; K6C antibody; K6c keratin antibody; K6d keratin antibody; K6e keratin antibody; Keratin antibody; Keratin K6h antibody; Keratin type II cytoskeletal 6A antibody; Keratin type II cytoskeletal 6B antibody; Keratin type II cytoskeletal 6C antibody; Keratin type II cytoskeletal 6D antibody; Keratin type II cytoskeletal 6E antibody; Keratin-6C antibody; KRT6A antibody; KRT6B antibody; KRT6C antibody; KRT6D antibody; KRT6E antibody; type II cytoskeletal 6C antibody; Type-II keratin Kb12 antibody; anti-KRT6A antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
SN71-07
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-KRT6A antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining Cytokeratin 6 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining Cytokeratin 6 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 6 antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 6 antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of Cytokeratin 6 on human skin lysates using anti-Cytokeratin 6 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of Cytokeratin 6 on human skin lysates using anti-Cytokeratin 6 antibody at 1/1, 000 dilution.)
Related Product Information for anti-KRT6A antibody
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins, which are useful markers of tissue differentiation, also aid in the characterization of malignant tumors. IL-1 and TNFalpha induce transcription of cytokeratin 6 in epidermal keratinocytes via the C/EBP beta transcription factor. In humans, multiple isoforms of cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies.
Product Categories/Family for anti-KRT6A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
564
NCBI Official Full Name
Keratin, type II cytoskeletal 6A
NCBI Official Synonym Full Names
keratin 6A
NCBI Official Symbol
KRT6A
NCBI Official Synonym Symbols
K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; KRT6C; KRT6D
NCBI Protein Information
keratin, type II cytoskeletal 6A; KDAMP; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; type-II keratin Kb6; keratin, epidermal type II, K6A; kamp-keratin derived antimicrobial peptide
UniProt Protein Name
Keratin, type II cytoskeletal 6A
UniProt Gene Name
KRT6A
UniProt Synonym Gene Names
K6A; KRT6D; CK-6A; CK-6D; K6A
UniProt Entry Name
K2C6A_HUMAN
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Product Notes
The KRT6A krt6a (Catalog #AAA312302) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cytokeratin 6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 6 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KRT6A krt6a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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