FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells with DHX58 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
Mouse anti-Human DHX58 Monoclonal Antibody | anti-DHX58 antibody
DHX58 Antibody
Gene Names
DHX58; LGP2; RLR-3; D11LGP2; D11lgp2e
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
ProA affinity purified
Synonyms
DHX58, Antibody; DHX58 Antibody; D11LGP2 antibody; D11lgp2e antibody; DEXH (Asp Glu X His) box polypeptide 58 antibody; DEXH box polypeptide 58 antibody; DHX 58 antibody; DHX58 antibody; DHX58_HUMAN antibody; LGP 2 antibody; LGP2 antibody; Ortholog of mouse D11lgp2 antibody; Probable ATP dependent helicase LGP2 antibody; Probable ATP dependent RNA helicase DHX58 antibody; Probable ATP-dependent helicase LGP2 antibody; Probable ATP-dependent RNA helicase DHX58 antibody; Protein D11Lgp2 homolog antibody; RIG-I-like receptor LGP2 antibody; RLR antibody; RNA helicase LGP2 antibody; anti-DHX58 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
A3-A6
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-DHX58 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot)
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells with DHX58 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of Hela cells with DHX58 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
WB (Western Blot)
(Western blot analysis of DHX58 on HEK293 (1) and DHX58-hIgGFc transfected HEK293 (2) cell lysate using anti-DHX58 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of DHX58 on HEK293 (1) and DHX58-hIgGFc transfected HEK293 (2) cell lysate using anti-DHX58 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of DHX58 on human DHX58 recombinant protein using anti-DHX58 antibody at 1/1, 000 dilution.)
WB (Western Blot)
(Western blot analysis of DHX58 on human DHX58 recombinant protein using anti-DHX58 antibody at 1/1, 000 dilution.)
Related Product Information for anti-DHX58 antibody
Helicases are enzymes that catalyze the separation of double stranded DNA or RNA by utilizing ATP. LGP2, also known as probable ATP-dependent RNA helicase DHX58, is a 678 amino acid protein belonging to the helicase family. LGP2 acts as a negative regulator of host innate immune defense against viruses by binding dsRNA produced during viral replication. The repressor domain of LGP2 binds to RIG-I, a signaling protein involved in host defenses against hepatitis C virus (HCV). By preventing RIG-I multimerization, LGP2 negatively regulates RIG-I-mediated signaling. Localized to the cytoplasm, LGP2 contains one helicase ATP-binding domain and one helicase C-terminal domain.
Product Categories/Family for anti-DHX58 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
76,613 Da
NCBI Official Full Name
likely ortholog of mouse D11lgp2, isoform CRA_b
NCBI Official Synonym Full Names
DEXH (Asp-Glu-X-His) box polypeptide 58
NCBI Official Symbol
DHX58
NCBI Official Synonym Symbols
LGP2; RLR-3; D11LGP2; D11lgp2e
NCBI Protein Information
probable ATP-dependent RNA helicase DHX58; RLR; RNA helicase LGP2; RIG-I-like receptor 3; protein D11Lgp2 homolog; RIG-I-like receptor LGP2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2
UniProt Protein Name
Probable ATP-dependent RNA helicase DHX58
UniProt Gene Name
DHX58
UniProt Synonym Gene Names
D11LGP2E; LGP2; RLR-3; RLR
UniProt Entry Name
DHX58_HUMAN
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Product Notes
The DHX58 dhx58 (Catalog #AAA312047) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The DHX58 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DHX58 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the DHX58 dhx58 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DHX58, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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