Mouse anti-Human EGFR Monoclonal Antibody | anti-EGFR antibody

EGFR

Cat. Num. AAA13559

• Gene Names: EGFR; ERBB; HER1; mENA; ERBB1; PIG61
• Reactivity: Human
• Synonyms: EGFR, Antibody; EGFR; anti-EGFR antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 31G7
• Form/Format: EGFR is a Mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.

• Immunogen: EGFR derived from A-431 cells.
• Localization: Cell Membrane
• Control: Skin, Placenta, Testis, Tonsil, Pancreas, Squamos, Cell Carcinoma
• Reactivity: Paraffin, Frozen
• Intended Use: Analyte Specific Reagent; ; Analytical and performance characteristics for EGFR antibody, clone 31G7 are not established.
• Reactivity: Paraffin, Frozen.
• Precautions: 1.- For professional users only. Ensure results are interpreted by a medical professional. ; 2.- This product contains sodium azide (NAN₃,a toxic chemical which may react with this plumbing to form highly explosive build-ups o f metal azides. Upon dipsosal, flush with large volumes of water to prevent sodium azide build- up.; 3.-Ensure proper handling procedures are used with reagent. Alwayswear proper laboratory equipment such as laboratory coat and gloves when hangling reagents. ; 4.- Unused solution should be disposed of acording to local and federal regulations. ; 5.- Do not ingest reagent. If reagent ingested, contact poison control center inmediately,; 6.- For complete recommendations for hnadling biological specimens please refer to the CDC document, ''Guidelines for Safe Wrok Practives in Human and Animal Laboratories''.
• Specimen Preparation: Paraffin sections: The antibody can be used on formalin-fixed paraffin-embedded (FFPE) tissue sections. Ensure tissue undergoes appropriate fixation and preparation to ensure best results.; ; Frozen sections and cell preparations: The antibody can be used for labeling acetone-fixed frozen sections and acetone-fixed cell preparations
• Preparation and Storage: Store at 2-8 °C. Do not use after expiration date listed on package label. Temperature fluctuations should be avoided. Store appropriately when not in use, and avoid prolonged exposure to room temperature conditions.

Application Data

IHC (Immunohistochemistry)

(IHC of EGFR on an FFPE Colon Carcinoma Tissue)

Related Product Information for anti-EGFR antibody

Epidermal Growth Factor Receptor (EGFR) is the receptor for epidermal growth factor (EGF). It is a member of the ErbB family receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER-2 neu (ErbB-2), HER-3 (ErbB-3) and HER-4 (ErbB-4).

NCBI and Uniprot Product Information

• NCBI GI #: 29725609
• NCBI GeneID: 1956
• NCBI Accession #: NP_005219.2
• NCBI GenBank Nucleotide #: NM_005228.3
• UniProt Accession #: P00533; O00688; O00732; P06268; Q14225; Q68GS5; Q92795; Q9BZS2; Q9GZX1; Q9H2C9; Q9H3C9; Q9UMD7; Q147T7; Q2TTR7; Q504U8; Q59FL8; Q68GS6; Q75MF2; Q8WZA5; Q9H3C8
• NCBI Official Full Name: epidermal growth factor receptor isoform a
• NCBI Official Synonym Full Names: epidermal growth factor receptor
• NCBI Official Symbol: EGFR
• NCBI Official Synonym Symbols: ERBB; HER1; mENA; ERBB1; PIG61
• NCBI Protein Information: epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
• UniProt Protein Name: Epidermal growth factor receptor
• UniProt Gene Name: EGFR
• UniProt Synonym Gene Names: ERBB1
• UniProt Entry Name: EGFR_HUMAN