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IHC (Immunohistchemistry)
(ERG Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Mouse anti-Human ERG Monoclonal Antibody | anti-ERG antibody
ERG Mouse anti-Human Monoclonal (8A9) Antibody
Gene Names
ERG; p55; erg-3
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Protein A/G purified
Synonyms
ERG; Monoclonal Antibody; ERG Mouse anti-Human Monoclonal (8A9) Antibody; PathPlus ERG Antibody (clone 8A9); ERG-3; Ets-related; TMPRSS2/ERG fusion; Transcriptional regulator ERG; p55; Transforming protein ERG; anti-ERG antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
8A9
Specificity
Human ERG
Purity/Purification
Protein A/G purified
Form/Format
PBS, pH7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-ERG antibody
Immunofluorescence (IF), Immunohistochemistry-Paraffin (IHC-P), Western Blot (WB)
Target
Human ERG
Immunogen
Full length human recombinant protein of human ERG(NP_891548) produced in HEk293T cell.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze-thaw cycles.
IHC (Immunohistchemistry)
(ERG Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistchemistry)
(ERG Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(ERG Antibody-Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
WB (Western Blot)
(ERG Antibody-HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERG (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ERG.)
WB (Western Blot)
(ERG Antibody-HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERG (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ERG.)
Related Product Information for anti-ERG antibody
ERG antibody is an unconjugated mouse monoclonal antibody to human ERG. Validated for IF, IHC and WB.
ERG (ETS Transcription Factor) is a member of the erythroblast transformation-specific family of transcription factors that act as key regulators of embryogenesis, differentiation, cell proliferation, angiogenesis, inflammation, and apoptosis. This protein contains an ETS DNA-binding domain and a PNT domain which is implicated in the self-association of chimeric oncoproteins. ERG is required for platelet adhesion to the endothelium during vascular remodeling, and is involved in the maturation of megakaryocytes. Chromosomal translocations between ERG and various genes are implicated in prostate cancer, Ewing's sarcoma, and acute myeloid leukemia. The normal protein is expressed in the nucleus and cytoplasm of a variety of tissues.
ERG (ETS Transcription Factor) is a member of the erythroblast transformation-specific family of transcription factors that act as key regulators of embryogenesis, differentiation, cell proliferation, angiogenesis, inflammation, and apoptosis. This protein contains an ETS DNA-binding domain and a PNT domain which is implicated in the self-association of chimeric oncoproteins. ERG is required for platelet adhesion to the endothelium during vascular remodeling, and is involved in the maturation of megakaryocytes. Chromosomal translocations between ERG and various genes are implicated in prostate cancer, Ewing's sarcoma, and acute myeloid leukemia. The normal protein is expressed in the nucleus and cytoplasm of a variety of tissues.
References
Medical Epigenetics 2015 3:19; Biochem Soc Trans 2009 37(pt6):1248; Science 2005 310:644
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,541 Da
NCBI Official Full Name
transcriptional regulator ERG isoform 2
NCBI Official Synonym Full Names
v-ets avian erythroblastosis virus E26 oncogene homolog
NCBI Official Symbol
ERG
NCBI Official Synonym Symbols
p55; erg-3
NCBI Protein Information
transcriptional regulator ERG; ets-related; TMPRSS2/ERG fusion; v-ets erythroblastosis virus E26 oncogene like; v-ets erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; transcriptional regulator ERG (tran
UniProt Protein Name
Transcriptional regulator ERG
UniProt Gene Name
ERG
UniProt Entry Name
ERG_HUMAN
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Product Notes
The ERG erg (Catalog #AAA21350) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ERG Mouse anti-Human Monoclonal (8A9) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ERG can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry-Paraffin (IHC-P), Western Blot (WB). Researchers should empirically determine the suitability of the ERG erg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERG, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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