Mouse anti-Human FGFR-2 (IIIB) Monoclonal Antibody | anti-FGFR-2 antibody
FGFR-2 (IIIB)
Reactivity
Human
Applications
Western Blot
Purity
Protein G chromatography
Synonyms
FGFR-2 (IIIB), Antibody; FGFR-2 (IIIB); Fgfr2; Bek; svs; KGFR; Fgfr7; Fgfr-2; Fgfr-7; KGFRTr; AU043015; AW556123; anti-FGFR-2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5F48
Purity/Purification
Protein G chromatography
Form/Format
lyophilized; PBS
Applicable Applications for anti-FGFR-2 antibody
WB (Western Blot)
Antigen
Human recombinant FGF-R2 isoforms EC domain
Reconstitution
Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml.
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Related Product Information for anti-FGFR-2 antibody
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig) like domains, an acidbox region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosinekinase domain. Multiple forms of FGF R1-3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. Only the alpha isoform has been identified for FGF R3 and FGF R4. Additional splicing events for FGF R13, involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons, generate FGF receptors with alternative IgIII domains (IIIb and IIIc). A IIIa isoform which is a secreted FGF binding protein containing only the N-terminal half of the IgIII domain plus some intron sequences has also been reported for FGF R1. Mutations in FGF R13 have been found in patients with birth defects involving craniosynostosis. The complex patterns of expression of these receptors as well as the specificity of their interactions with the various FGF ligand family members are under permanent investigation.
NCBI and Uniprot Product Information
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Product Notes
The FGFR-2 fgfr2 (Catalog #AAA79332) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FGFR-2 (IIIB) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FGFR-2 (IIIB) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the FGFR-2 fgfr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGFR-2 (IIIB), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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