SDS-PAGE
(SDS-PAGE Analysis Purified FSH Receptor Mouse Monoclonal Antibody (FSHR/1400). Confirmation of Purity and Integrity of Antibody.)
Mouse anti-Human FSH-Receptor Monoclonal Antibody | anti-FSHR antibody
FSH-Receptor (Ovarian Marker)
Gene Names
FSHR; LGR1; ODG1; FSHR1; FSHRO
Reactivity
Human
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
FSH-Receptor, Antibody; FSH-Receptor (Ovarian Marker); Follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; FSH-R; FSHRO; LGR1; ODG1; ovarian dysgenesis 1; anti-FSHR antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
FSHR/1400
Specificity
Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome; a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
695
Applicable Applications for anti-FSHR antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant human full-length FSHR protein
Cellular Localization
Cytoplasmic & Cell Surface
Hu-chromosome Location
2p21-p16
Positive Control
Uterine Carcinoma
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Non-hazardous. No MSDS required.
Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified FSH Receptor Mouse Monoclonal Antibody (FSHR/1400). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified FSH Receptor Mouse Monoclonal Antibody (FSHR/1400). Confirmation of Purity and Integrity of Antibody.)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Breast Invasive Ductal Carcinoma stained with Estrogen Receptor Monoclonal Antibody (ER506).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Breast Invasive Ductal Carcinoma stained with Estrogen Receptor Monoclonal Antibody (ER506).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Uterine Carcinoma stained with FSH Receptor Monoclonal Antibody (FSHR/1400).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Uterine Carcinoma stained with FSH Receptor Monoclonal Antibody (FSHR/1400).)
References
Beau, I., et al. 1998. The basolateral localization signal of the follicle-stimulating hormone receptor. J. Biol. Chem. 273: 18610-18616.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75kDa
NCBI Official Full Name
follicle-stimulating hormone receptor isoform 1
NCBI Official Synonym Full Names
follicle stimulating hormone receptor
NCBI Official Symbol
FSHR
NCBI Official Synonym Symbols
LGR1; ODG1; FSHR1; FSHRO
NCBI Protein Information
follicle-stimulating hormone receptor
UniProt Protein Name
Follicle-stimulating hormone receptor
UniProt Gene Name
FSHR
UniProt Synonym Gene Names
LGR1; FSH-R
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Product Notes
The FSHR fshr (Catalog #AAA62988) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FSH-Receptor (Ovarian Marker) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FSH-Receptor can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the FSHR fshr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FSH-Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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