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Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Mouse HP-1gamma Monoclonal Antibody | anti-HP-1gamma antibody
HP-1gamma mouse Monoclonal Antibody (3B9)
Gene Names
CBX3; HECH; HP1-GAMMA; HP1Hs-gamma
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Synonyms
HP-1gamma; Monoclonal Antibody; HP-1gamma mouse Monoclonal Antibody (3B9); Chromobox protein homolog 3 (HECH)(Heterochromatin protein 1 homolog gamma)(HP1 gamma)(Modifier 2 protein); anti-HP-1gamma antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
3B9
Applicable Applications for anti-HP-1gamma antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Application Data
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
WB (Western Blot)
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
WB (Western Blot)
(Dilution: WB 1:500-2000,IHC-p 1:50-300)
Related Product Information for anti-HP-1gamma antibody
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1. Mediates the recruitement of NIPBL to sites of DNA damage at double-strand breaks (DSBs)(PubMed:28167679).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,811 Da
NCBI Official Full Name
chromobox protein homolog 3
NCBI Official Synonym Full Names
chromobox homolog 3
NCBI Official Symbol
CBX3
NCBI Official Synonym Symbols
HECH; HP1-GAMMA; HP1Hs-gamma
NCBI Protein Information
chromobox protein homolog 3; HP1 gamma homolog; modifier 2 protein; heterochromatin-like protein 1; heterochromatin protein HP1 gamma; heterochromatin protein 1 homolog gamma; chromobox homolog 3 (HP1 gamma homolog, Drosophila)
UniProt Protein Name
Chromobox protein homolog 3
UniProt Gene Name
CBX3
UniProt Synonym Gene Names
HP1 gamma
UniProt Entry Name
CBX3_HUMAN
Similar Products
Product Notes
The HP-1gamma cbx3 (Catalog #AAA28914) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HP-1gamma mouse Monoclonal Antibody (3B9) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HP-1gamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). Researchers should empirically determine the suitability of the HP-1gamma cbx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HP-1gamma, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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