Rat IL-6 Monoclonal Antibody | anti-Il6 (Mouse) antibody
IL-6 (Mouse)
Gene Names
Il6; Il-6
Reactivity
Mouse. Does not react with human and rat.
Applications
Immunofluorescence, Flow Cytometry, Functional Assay, Neutralization Assay
Synonyms
IL-6, Antibody; IL-6 (Mouse); B cell differentiation factor; B-cell stimulatory factor 2 (BSF-2); CTL differentiation factor (CDF); Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HPGF; HSF; Hybridoma growth factor (HGF); Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; IFN-beta-2; IFNB2; Interferon beta-2; Interleukin 6 (interferon beta 2); anti-Il6 (Mouse) antibody
Host
Rat
Reactivity
Mouse. Does not react with human and rat.
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
MP5-20F3
Specificity
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.
Form/Format
1.0mg/mL of Ab Purified from Biocreactor Concentrate by Protein A/G.
Sequence Length
211
Applicable Applications for anti-Il6 (Mouse) antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry), NTRL (Neutralization)
Localization
Cytoplasmic and extracellular (secreted)
Positive Control
Mouse heart
Human Chromosomal Location
5 B1 (Mouse)
Immunogen
Recombinant mouse IL-6 protein
Cellular Localization
Cytoplasmic and extracellular (secreted)
Preparation and Storage
Antibody without azide store at -20°C to -80°C. Non-hazardous . No MSDS required.
References
1. Abrams J, et al. 1992. Immunol. Rev. 127:5. (ELISA Capture, Neut)
2. Sander B, et al. 1993. J. Immunol. Meth. 166:201. (ELISA Capture, Neut)
3. Abrams J, 1995. Curr. Prot. Immunol. John Wiley and Sons, New York. Unit 6.20. (ELISA Capture)
4. Litton M, et al. 1994. J. Immunol Meth. 175:47. (IHC)
5. Finkelman F, et al. 2003. Curr. Prot. Immunol. John Wiley & Sons, New York. Unit 6.28. (In Vivo Capture)
6. Starnes HF Jr, et al. 1990. J. Immunol. 145:4185. (Neut)
7. Riedemann NC, et al. 2003. J. Immunol. 170:503. (Neut)
8. Rochman I, et al. 2005. J. Immunol. 174:4761. (Neut)
9. O'Connell PJ, et al. 2006. Blood 107:1010. (ELISA Capture)
2. Sander B, et al. 1993. J. Immunol. Meth. 166:201. (ELISA Capture, Neut)
3. Abrams J, 1995. Curr. Prot. Immunol. John Wiley and Sons, New York. Unit 6.20. (ELISA Capture)
4. Litton M, et al. 1994. J. Immunol Meth. 175:47. (IHC)
5. Finkelman F, et al. 2003. Curr. Prot. Immunol. John Wiley & Sons, New York. Unit 6.28. (In Vivo Capture)
6. Starnes HF Jr, et al. 1990. J. Immunol. 145:4185. (Neut)
7. Riedemann NC, et al. 2003. J. Immunol. 170:503. (Neut)
8. Rochman I, et al. 2005. J. Immunol. 174:4761. (Neut)
9. O'Connell PJ, et al. 2006. Blood 107:1010. (ELISA Capture)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21kDa
NCBI Official Full Name
interleukin-6
NCBI Official Synonym Full Names
interleukin 6
NCBI Official Symbol
Il6
NCBI Official Synonym Symbols
Il-6
NCBI Protein Information
interleukin-6; interleukin HP-1; B-cell hybridoma growth factor
UniProt Protein Name
Interleukin-6
UniProt Gene Name
Il6
UniProt Synonym Gene Names
Il-6; IL-6
UniProt Entry Name
IL6_MOUSE
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Product Notes
The Il6 (Mouse) il6 (Catalog #AAA62636) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The IL-6 (Mouse) reacts with Mouse. Does not react with human and rat. and may cross-react with other species as described in the data sheet. AAA Biotech's IL-6 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry), NTRL (Neutralization). Researchers should empirically determine the suitability of the Il6 (Mouse) il6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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