IHC (Immunohiostchemistry)
(Immunohistochemical of Keap1 in Human breast cancer tissue using Keap1 antibody at dilution 1:20)
Rabbit anti-Human, Mouse Keap1 Monoclonal Antibody | anti-Keap1 antibody
Recombinant Keap1 Monoclonal Antibody
Gene Names
KEAP1; INrf2; KLHL19
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Keap1, Antibody; Recombinant Keap1 Monoclonal Antibody; Cytosolic inhibitor of Nrf2; INrf 2; INrf2; Keap 1; KEAP1; Kelch like ECH associated protein 1; Kelch like family member 19; Kelch like protein 19; Kelch-like ECH-associated protein 1; Kelch-like protein 19; KIAA0132; KLHL 19; KLHL19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454; anti-Keap1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
R02-1H7
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Concentration
300ug/mL (varies by lot)
Applicable Applications for anti-Keap1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human Keap1
Research Area
Cancer, Epigenetics and Nuclear Signaling
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical of Keap1 in Human breast cancer tissue using Keap1 antibody at dilution 1:20)
IHC (Immunohiostchemistry)
(Immunohistochemical of Keap1 in Human breast cancer tissue using Keap1 antibody at dilution 1:20)
WB (Western Blot)
(Western blot detection of Keap1 in Hela,A549,C2C12 cell lysates using Keap1 Rabbit mAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:60-64kDa.)
WB (Western Blot)
(Western blot detection of Keap1 in Hela,A549,C2C12 cell lysates using Keap1 Rabbit mAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:60-64kDa.)
Related Product Information for anti-Keap1 antibody
KEAP1,also named as INRF2,KIAA0132 and KLHL19,is part of a multiprotein complex that contains the CUL3-ROC1 ubiquitin ligase,which can ubiquitinate the N-terminal domain of NRF2. Two molecules of KEAP1 bind to two distinct sites in the N-terminal region of NRF2,theETGE and DLG sites,which affect the KEAP1-NRF2 interaction and/or its physiological consequences. KEAP1 retains NFE2L2/NRF2 in the cytosol. It functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. It also retains BPTF in the cytosol. This antibody is mouse monoclonal antibody raised against residues near the C terminus of human KEAP1.
Product Categories/Family for anti-Keap1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
624
NCBI Official Full Name
Kelch-like ECH-associated protein 1
NCBI Official Synonym Full Names
kelch-like ECH-associated protein 1
NCBI Official Symbol
KEAP1
NCBI Official Synonym Symbols
INrf2; KLHL19
NCBI Protein Information
kelch-like ECH-associated protein 1; kelch-like protein 19; cytosolic inhibitor of Nrf2; kelch-like family member 19
UniProt Protein Name
Kelch-like ECH-associated protein 1
UniProt Gene Name
KEAP1
UniProt Synonym Gene Names
INRF2; KIAA0132; KLHL19; INrf2
UniProt Entry Name
KEAP1_HUMAN
Similar Products
Product Notes
The Keap1 keap1 (Catalog #AAA178819) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Keap1 Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Keap1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Keap1 keap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Keap1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.