Application Data
Mouse anti-Chicken MHC Class II Monoclonal Antibody | anti-HLA-DQB1 antibody
Mouse Anti-Chicken MHC Class II-PE
Gene Names
HLA-DQB1; IDDM1; CELIAC1; HLA-DQB
Reactivity
Chicken
Applications
Immunoprecipitation, Immunohistochemistry, Immunoblot, Western Blot, Flow Cytometry, Functional Assay
Synonyms
MHC Class II, Antibody; Mouse Anti-Chicken MHC Class II-PE; Mouse Anti-Chicken MHC Class II - Phycoerythrin-Labeled; Mouse Anti-Chicken MHC Class II; anti-HLA-DQB1 antibody
Host
Mouse
Reactivity
Chicken
Clonality
Monoclonal
Isotype
Mouse IgG1 kappa
Clone Number
2G11
Specificity
Chicken MHC Class II (B-L) molecules
Form/Format
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
Sequence Length
229
Applicable Applications for anti-HLA-DQB1 antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), IB (Immunoblot), FCM/FACS (Flow Cytometry)
Preparation and Storage
Store at 2- 8°C.
Application Data
Application Data
Related Product Information for anti-HLA-DQB1 antibody
The chicken major histocompatibility complex (MHC), or B complex, consists of several clusters of highly polymorphic genes. Like their mammalian counterparts, the avian MHC exerts genetic influence over a variety of important biological functions such as immune response, disease resistance, growth and development, aging, and reproduction. Chicken MHC Class II genes, also known as the B-L subregion, of the chicken MHC encode cell surface glycoproteins that are homologous to mammalian Class II antigens. B-L antigens structurally are similar to mammalian Class II molecules in that they are noncovalently bound dimmers of one 32-34 kDa heavy chain and one 27-30 kDa light chain. MHC Class II is primarily expressed on B cells and antigen presenting cells (APCs).
References
1. Guillemot, F., P. Turmal, D. Charron, M. Le Douarin, and C. Auffray. 1986. J. Immunol. 137:1251.
2. Lawson, S., L. Rothwell, B. Lambrecht, K. Howes, K. Venugopal, and P. Kaiser. 2001. Dev. Comp. Immunol. 25:69.
3. Koritschoner, N.P., J. Madruga, S. Knespel, G. Blendinger, B. Anzinger, A. Otto, M. Zenke, and P. Bartunek. 2001. Cell Growth Differ. 12:563.
4. Katevuo, K., and O. Vainio. 1996. Immunol. 89:419.
5. Madruga, J., N. Koritschoner, S.S. Diebold, S.M. Kurz, and M. Zenke. 1999. J. Cell Sci. 112:1685.
6. Salomonsen, J., D. Dunon, K. Skjodt, D. Thorpe, O. Vainio, and J. Kaufman. 1991. Proc. Natl. Acad. Sci. USA. 88:1359.
7. Kaufman, J., K.Skjoedt, J. Salomonsen, M. Simonsen, L. Du Pasquier, R. Parisot, and P. Riegert. 1990. J. Immunol. 144:2258.
2. Lawson, S., L. Rothwell, B. Lambrecht, K. Howes, K. Venugopal, and P. Kaiser. 2001. Dev. Comp. Immunol. 25:69.
3. Koritschoner, N.P., J. Madruga, S. Knespel, G. Blendinger, B. Anzinger, A. Otto, M. Zenke, and P. Bartunek. 2001. Cell Growth Differ. 12:563.
4. Katevuo, K., and O. Vainio. 1996. Immunol. 89:419.
5. Madruga, J., N. Koritschoner, S.S. Diebold, S.M. Kurz, and M. Zenke. 1999. J. Cell Sci. 112:1685.
6. Salomonsen, J., D. Dunon, K. Skjodt, D. Thorpe, O. Vainio, and J. Kaufman. 1991. Proc. Natl. Acad. Sci. USA. 88:1359.
7. Kaufman, J., K.Skjoedt, J. Salomonsen, M. Simonsen, L. Du Pasquier, R. Parisot, and P. Riegert. 1990. J. Immunol. 144:2258.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
MHC class II
NCBI Official Synonym Full Names
major histocompatibility complex, class II, DQ beta 1
NCBI Official Symbol
HLA-DQB1
NCBI Official Synonym Symbols
IDDM1; CELIAC1; HLA-DQB
NCBI Protein Information
HLA class II histocompatibility antigen, DQ beta 1 chain; MHC DQ beta; MHC class2 antigen; OTTHUMP00000029167; OTTHUMP00000178569; OTTHUMP00000178570; OTTHUMP00000178571; lymphocyte antigen; MHC class II antigen DQB1; MHC class II DQ beta chain; MHC class II antigen HLA-DQ-beta-1; MHC class II HLA-DQ beta glycoprotein; major histocompatibility complex class II beta; HLA class II histocompatibility antigen, DQ beta 1 chain-like
UniProt Protein Name
MHC class II HLA-DQ-beta-1
UniProt Gene Name
HLA-DQB1
UniProt Entry Name
O19707_HUMAN
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Product Notes
The HLA-DQB1 hla-dqb1 (Catalog #AAA78706) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Chicken MHC Class II-PE reacts with Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's MHC Class II can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), IB (Immunoblot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the HLA-DQB1 hla-dqb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MHC Class II, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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