Mouse MHC Class II Monoclonal Antibody | anti-MHC Class II antibody
MHC Class II, Mouse Anti Human
Applications
Immunoprecipitation, Western Blot, Flow Cytometry, Functional Assay
Purity
Ion exchange column.
Synonyms
MHC Class II, Antibody; MHC Class II, Mouse Anti Human; MHC Class II Antibody; MHC Class II, Mouse Anti-Human; anti-MHC Class II antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
CYR-hClass II
Specificity
All haplotypes.
Purity/Purification
Ion exchange column.
Concentration
1mg/ml in PBS (after reconstitution). (varies by lot)
Sequence Length
229
Applicable Applications for anti-MHC Class II antibody
IP (Immunoprecipitation), WB (Western Blot), FCM/FACS (Flow Cytometry)
Physical Appearance
Sterile filtered white lyophilized (freeze-dried) powder.
Reconstitution
Reconstitute with of H2O mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Titer
Staining anitbody. For staining, use 10ul/10^6 cells.
Immunogen
Purified Human B cells.
Available Conjugates
This antibody is currently available only as purified antibody.
Preparation and Storage
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
Shipping Condition: Antibody is shipped lyophilized at ambient temperature.
Antibody is shipped lyophilized at ambient temperature.
Shipping Condition: Antibody is shipped lyophilized at ambient temperature.
Related Product Information for anti-MHC Class II antibody
Introduction: MHC Class II is consists of 2 membrane spanning proteins. Each of these proteins is roughly 30 kDa, and has of two Globular domains, Alpha-1, Alpha-2, Beta-1 and Beta-2. The two regions farthest away from the membrane are alpha-1 and beta-1. The two proteins link without Covalent Bonds. The MHC Class II protein mainly presents peptides, which have been digested from external sources. MHC Class II is normally only expressed by Antigen Presenting Cells (APC) which digest foreign protein. Within the RER the alpha and beta proteins of the molecule, associate with each other, while a third protein called the "invariant chain," is necessary for stabilizing the complex, without it, they will not associate. The MHC-invariant complex is then passed from the RER, into and out of, the Golgi body. It fuses with an Endocytic compartment, where an external protein has been sampled and degraded.
Product Categories/Family for anti-MHC Class II antibody
References
Natural CD4+ T-cell responses against indoleamine 2, 3-dioxygenase. Shamaila Munir, Stine Kiaer Larsen, Trine Zeeberg Iversen, Marco Donia, Tobias Wirenfeldt Klausen, Inge Marie Svane, Per thor Straten, Mads Hald Andersen (2012)
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
26,489 Da
NCBI Official Full Name
MHC class II HLA-DQ-beta-1
UniProt Protein Name
MHC class II HLA-DQ-beta-1
UniProt Gene Name
HLA-DQB1
UniProt Entry Name
O19707_HUMAN
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Product Notes
The MHC Class II hla-dqb1 (Catalog #AAA37947) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MHC Class II can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the MHC Class II hla-dqb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MHC Class II, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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