Rabbit anti-Human mtTFA Monoclonal Antibody | anti-mtTFA antibody

Recombinant mtTFA Monoclonal Antibody

Cat. Num. AAA178867

• Gene Names: TFAM; TCF6; MTTF1; MTTFA; TCF6L1; TCF6L2; TCF6L3
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity Purified
• Synonyms: mtTFA, Antibody; Recombinant mtTFA Monoclonal Antibody; anscription factor 6-like 1; Mitochondrial transcription factor 1; mitochondrial transcription factor A; MtTF1; mtTFA; TCF 6; TCF-6; TCF6; TCF6L1; TCF6L2; TCF6L3; TFAM; Transcription factor 6; Transcription factor 6 like 2 (mitochondrial transcription factor); Transcription factor 6 like 2; Transcription factor 6-like 2; transcription factor 6-like 3; Transcription factor A; mitochondrial; mitochondrial precursor; anti-mtTFA antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG
• Clone Number: R08-3E2
• Purity/Purification: Affinity Purified
• Form/Format: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
• Concentration: 300ug/mL (varies by lot)

• Applicable Applications for anti-mtTFA antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: A synthetic peptide of human mtTFA
• Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction, Tags and Cell Markers
• Preparation and Storage: Storage: -20 degree C/One year. Avoid freeze/thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochemistry of mtTFA in paraffin-embedded Human breast cancer tissue using mtTFA Rabbit mAb at dilution 1:100)

WB (Western Blot)

(Western blot detection of mtTFA in K562,Hela cell lysates using mtTFA Rabbit mAb(1:1000 diluted).Predicted band size:29kDa.Observed band size:24kDa.)

IF (Immunofluorescence)

(Immunofluorescence of mtTFA/TFAM(green) in Hela cells using mtTFA/TFAM Rabbit mAb at dilution 1:200, and DAPI(blue))

Related Product Information for anti-mtTFA antibody

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.TFAM (Transcription Factor A, Mitochondrial) is Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.

Product Categories/Family for anti-mtTFA antibody

Antibodies; Primary Antibodies; Recombinant Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 4507401
• NCBI GeneID: 7019
• NCBI Accession #: NP_003192.1
• NCBI GenBank Nucleotide #: NM_003201.2
• UniProt Accession #: Q00059; Q5U0C6; A9QXC6; B5BU05
• Molecular Weight: 29,097 Da
• NCBI Official Full Name: transcription factor A, mitochondrial isoform 1
• NCBI Official Synonym Full Names: transcription factor A, mitochondrial
• NCBI Official Symbol: TFAM
• NCBI Official Synonym Symbols: TCF6; MTTF1; MTTFA; TCF6L1; TCF6L2; TCF6L3
• NCBI Protein Information: transcription factor A, mitochondrial; transcription factor 6; transcription factor 6-like 1; transcription factor 6-like 3; mitochondrial transcription factor 1; mitochondrial transcription factor A; transcription factor 6-like 2 (mitochondrial transcrip
• UniProt Protein Name: Transcription factor A, mitochondrial
• UniProt Gene Name: TFAM
• UniProt Synonym Gene Names: TCF6; TCF6L2; mtTFA; MtTF1; TCF-6
• UniProt Entry Name: TFAM_HUMAN